(1)
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产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF4808, RRID:AB_2837159.
展开/折叠
C lectin type II protein; CD159 antigen like family member A; CD159 antigen-like family member A; CD159a; CD159a antigen; Killer cell lectin like receptor subfamily C member 1; KLRC1; MGC13374; MGC59791; Natural killer cell lectin; Natural killer cell protein group 2-A1; Natural killer cell receptor NKG2A; Natural killer group protein 2; NK cell receptor A; NKG2 1/B activating NK receptor; NKG2 A; NKG2 A/B activating NK receptor; NKG2 A/B type II integral membrane protein; NKG2 A/NKG2 B type II integral membrane protein; NKG2; NKG2 B; NKG2-1/B activating NK receptor; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein; NKG2A; NKG2A_HUMAN; NKG2B; rNKG2A;
抗原和靶标
- P26715 NKG2A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDNQGVIYSDLNLPPNPKRQQRKPKGNKNSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSTLIQRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL
翻译修饰 - P26715 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y8 | Phosphorylation | Uniprot | |
| Y40 | Phosphorylation | Uniprot | |
| T89 | Phosphorylation | Uniprot | |
| S104 | Phosphorylation | Uniprot | |
| S105 | Phosphorylation | Uniprot | |
| T108 | Phosphorylation | Uniprot | |
| T110 | Phosphorylation | Uniprot | |
| K195 | Acetylation | Uniprot | |
| K199 | Acetylation | Uniprot |
研究背景
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Membrane>Single-pass type II membrane protein.
Natural killer cells.
Can form disulfide-bonded heterodimer with KLRD1. KLRD1-KLRC1 heterodimer interacts with peptide-bound HLA-E-B2M heterotrimeric complex.
研究领域
· Human Diseases > Immune diseases > Graft-versus-host disease.
· Organismal Systems > Immune system > Antigen processing and presentation. (View pathway)
· Organismal Systems > Immune system > Natural killer cell mediated cytotoxicity. (View pathway)
文献引用
Application: IHC Species: Human Sample: UCEC tumor and the adjacent tissues
Application: IHC Species: Human Sample: UCEC tumor and the adjacent tissues
Application: IHC Species: Human Sample: UCEC tumor and the adjacent tissues
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