产品: ATG16L2 抗体
货号: DF4817
描述: Rabbit polyclonal antibody to ATG16L2
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Bovine, Sheep, Rabbit
分子量: 69 KD; 69kD(Calculated).
蛋白号: Q8NAA4
RRID: AB_2837168

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Bovine(82%), Sheep(82%), Rabbit(91%)
克隆:
Polyclonal
特异性:
ATG16L2 Antibody detects endogenous levels of total ATG16L2.
RRID:
AB_2837168
引用格式: Affinity Biosciences Cat# DF4817, RRID:AB_2837168.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

A16L2_HUMAN; APG16-like 2; ATG16 autophagy related 16-like 2; ATG16B; Atg16l2; autophagy related 16-like 2 (S. cerevisiae); Autophagy-related protein 16-2; WD repeat-containing protein 80; WDR80;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MAGPGVPGAPAARWKRHIVRQLRLRDRTQKALFLELVPAYNHLLEKAELLDKFSKKLQPEPNSVTPTTHQGPWEESELDSDQVPSLVALRVKWQEEEEGLRLVCGEMAYQVVEKGAALGTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGPDTLGDGMRERRETLALAPEPEPLEKEACEKWKRPFRSASATSLTLSHCVDVVKGLLDFKKRRGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Rabbit
91
Bovine
82
Sheep
82
Pig
73
Horse
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q8NAA4 作为底物

Site PTM Type Enzyme
T232 Phosphorylation
S234 Phosphorylation
S236 Phosphorylation
T241 Phosphorylation
S278 Phosphorylation
S304 Phosphorylation
S441 Phosphorylation
T552 Phosphorylation
S557 Phosphorylation
S608 Phosphorylation

研究背景

功能:

May play a role in autophagy.

细胞定位:

Cytoplasm.
Note: Localizes also to discrete punctae along the ciliary axoneme.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
蛋白家族:

Belongs to the WD repeat ATG16 family.

研究领域

· Cellular Processes > Transport and catabolism > Autophagy - animal.   (View pathway)

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