ADORA3 Antibody - #DF4851

>>买2送1 进行中>>
>>满百送 进行中>>
>>赠送JD卡 进行中>>
>>3倍积分 进行中>>
(1)   (3)  
产品: ADORA3 抗体
货号: DF4851
描述: Rabbit polyclonal antibody to ADORA3
应用: WB IHC IF/ICC
反应: Human, Mouse
分子量: 38 KD; 36kD(Calculated).
蛋白号: P0DMS8
RRID: AB_2837215

浏览相似产品>>

   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

联系销售
相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
克隆:
Polyclonal
特异性:
ADORA3 Antibody detects endogenous levels of total ADORA3.
RRID:
AB_2837215
引用格式: Affinity Biosciences Cat# DF4851, RRID:AB_2837215.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

A3AR; A3R; AA3R; AA3R_HUMAN; AD 026; AD026; Adenosine A3 receptor; Adenosine receptor A3; ADORA 3; ADORA3; ARA3; bA552M11.5; Gpcr2; RP11 552M11.7; TGPCR1;

抗原和靶标

免疫原:
Uniprot:

P0DMS8(AA3R_HUMAN) >>Visit HPA database.

基因/基因ID:
ADORA3(140)
表达:
P0DMS8 AA3R_HUMAN:

Expressed in the lung and bone. Expressed at lower levels in osteosarcoma tissues (at protein level).

序列:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE

翻译修饰 - P0DMS8 作为底物

Site PTM Type Enzyme
S213 Phosphorylation

研究背景

功能:

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.

细胞定位:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in the lung and bone. Expressed at lower levels in osteosarcoma tissues (at protein level).

蛋白家族:

Belongs to the G-protein coupled receptor 1 family.

研究领域

· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Sphingolipid signaling pathway.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

文献引用

1). The cumulative analgesic effect of repeated electroacupuncture is modulated by Adora3 in the SCDH of mice with neuropathic pain. Animal models and experimental medicine, 2024 (PubMed: 38992885) [IF=3.7]

Application: WB    Species: Mouse    Sample:

FIGURE 2 Multiple electroacupuncture sessions influence the Spinal Adora3 and related enzymes. (A–C) Relative mRNA expression levels of Adora3, CD73, and ADA. (D) Western blot showing protein expression. (E–G) Relative protein expression levels of Adora3, CD73, ADA, and GAPDH. (H) Pearson's correlation analysis of Adora3 and metabolizing enzymes with the nociceptive responses. On days 2EA, 4EA, and 7EA following surgery, samples were obtained from the lumber L4–L6 segments. The data are presented as the means ± SD. Statistical significance was considered at p 

限制条款

产品的规格、报价、验证数据请以官网为准，官网链接：www.affbiotech.com | www.affbiotech.cn（简体中文）| www.affbiotech.jp（日本語）

产品的数据信息为Affinity所有，未经授权不得收集Affinity官网数据或资料用于商业用途，对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整，如您已订购该产品，请以订购时随货说明书为准，否则请以官网内容为准，官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时，请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.