| 产品: | RXFP3 抗体 |
| 货号: | DF5149 |
| 描述: | Rabbit polyclonal antibody to RXFP3 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Bovine, Sheep, Rabbit |
| 分子量: | 51 KD; 51kD(Calculated). |
| 蛋白号: | Q9NSD7 |
| RRID: | AB_2837339 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF5149, RRID:AB_2837339.
展开/折叠
G protein coupled receptor GPCR135; G protein coupled receptor SALPR; G protein-coupled receptor SALPR; G-protein coupled receptor GPCR135; GPCR 135; GPCR135; Gprotein coupled receptor SALPR; Relaxin 3 receptor 1; Relaxin 3 receptor1; Relaxin 3/INSL7 receptor 1; Relaxin 3/INSL7 receptor1; Relaxin family peptide receptor 3; Relaxin family peptide receptor3; Relaxin-3 receptor 1; Relaxin/insulin like family peptide receptor 3; Relaxin3 receptor 1; Relaxin3 receptor1; RL3 R1; RL3R 1; RL3R1; RL3R1_HUMAN; RLN3 receptor 1; RLN3 receptor1; RLN3R1; RXFP3; RXFPR3; SALP R; SALPR; somatostatin and angiotensin like peptide receptor; Somatostatin- and angiotensin-like peptide receptor;
抗原和靶标
Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
- Q9NSD7 RL3R1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTATTKPEHEDQGLQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9NSD7 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S269 | Phosphorylation | Uniprot | |
| R312 | Methylation | Uniprot | |
| R320 | Methylation | Uniprot | |
| Y460 | Phosphorylation | Uniprot | |
| Y469 | Phosphorylation | Uniprot |
研究背景
Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
Cell membrane>Multi-pass membrane protein.
Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
Belongs to the G-protein coupled receptor 1 family.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
· Organismal Systems > Endocrine system > Relaxin signaling pathway.
限制条款
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