产品: PEVR2 抗体
货号: DF5142
描述: Rabbit polyclonal antibody to PEVR2
应用: WB IF/ICC
反应: Human
分子量: 46 KD; 46kD(Calculated).
蛋白号: Q9NWF4
RRID: AB_2837501

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   规格 价格 库存
 50ul RMB¥ 1250 现货
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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
PEVR2 Antibody detects endogenous levels of total PEVR2.
RRID:
AB_2837501
引用格式: Affinity Biosciences Cat# DF5142, RRID:AB_2837501.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FLJ10060; G protein coupled receptor 172B; GPCR; GPCR42; hRFT1; member 1; OTTHUMP00000125300; PAR2; PERV-A receptor 2; PERVA receptor 2; Porcine endogenous retrovirus A receptor 2; Protein GPR172B; Putative G protein coupled receptor GPCR42; Riboflavin transporter 1; riboflavin transporter; S52A1_HUMAN; SLC52A1; Solute carrier family 52; Solute carrier family 52, riboflavin transporter, member 1;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q9NWF4 S52A1_HUMAN:

Widely expressed. Highly expressed in the testis, placenta and small intestine. Expressed at lower level in other tissues.

序列:
MAAPTLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKDLPEGWSLPSYLSVVVALGNLGLLVVTLWRQLAPGKGEQVPIQVVQVLSVVGTALLAPLWHHVAPVAGQLHSVAFLTLALVLAMACCTSNVTFLPFLSHLPPPFLRSFFLGQGLSALLPCVLALVQGVGRLECPPAPTNGTSGPPLDFPERFPASTFFWALTALLVTSAAAFRGLLLLLPSLPSVTTGGSGPELQLGSPGAEEEEKEEEEALPLQEPPSQAAGTIPGPDPEAHQLFSAHGAFLLGLMAFTSAVTNGVLPSVQSFSCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRSLAGLVGLSLLGMLFGAYLMALAILSPCPPLVGTTAGVVLVVLSWVLCLCVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGAGAMFPPTSIYHVFQSRKDCVDPCGP

翻译修饰 - Q9NWF4 作为底物

Site PTM Type Enzyme
K245 Ubiquitination

研究背景

功能:

Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption.

(Microbial infection) May function as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).

细胞定位:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Widely expressed. Highly expressed in the testis, placenta and small intestine. Expressed at lower level in other tissues.

蛋白家族:

Belongs to the riboflavin transporter family.

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