产品: MRGX3 抗体
货号: DF5177
描述: Rabbit polyclonal antibody to MRGX3
应用: WB IF/ICC
反应: Human
分子量: 34 KD; 36kD(Calculated).
蛋白号: Q96LB0
RRID: AB_2837526

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
MRGX3 Antibody detects endogenous levels of total MRGX3.
RRID:
AB_2837526
引用格式: Affinity Biosciences Cat# DF5177, RRID:AB_2837526.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

G protein coupled receptor SNSR1; G protein coupled receptor SNSR2; G protein-coupled receptor MRGX 3; G protein-coupled receptor MRGX3; GPCR; Mas related GPCR member X3; Mas-related G protein coupled MRGX 3; Mas-related G protein coupled MRGX3; Mas-related G-protein coupled receptor member X3; MAS-related GPR, member X3; MRGPRX3; MRGX3; MRGX3_HUMAN; Sensory neuron-specific G-protein coupled receptor 1; Sensory neuron-specific G-protein coupled receptor 1/2; SNSR1; SNSR2;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q96LB0 MRGX3_HUMAN:

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

序列:
MDSTIPVLGTELTPINGREETPCYKQTLSFTGLTCIVSLVALTGNAVVLWLLGCRMRRNAVSIYILNLVAADFLFLSGHIICSPLRLINIRHPISKILSPVMTFPYFIGLSMLSAISTERCLSILWPIWYHCRRPRYLSSVMCVLLWALSLLRSILEWMFCDFLFSGANSVWCETSDFITIAWLVFLCVVLCGSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGIQWALFSRIHLDWKVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDTPEVDEGGGWLPQETLELSGSRLEQ

研究背景

功能:

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).

细胞定位:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

蛋白家族:

Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

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