| 产品: | PTGDR 抗体 |
| 货号: | DF5213 |
| 描述: | Rabbit polyclonal antibody to PTGDR |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 分子量: | 40 KD; 40kD(Calculated). |
| 蛋白号: | Q13258 |
| RRID: | AB_2837562 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF5213, RRID:AB_2837562.
展开/折叠
AS 1; AS1; ASRT 1; ASRT1; DP; MGC49004; OTTHUMP00000178986; PD2R_HUMAN; PGD receptor; PGD2 receptor; Prostaglandin D2 receptor (DP); Prostaglandin D2 receptor; Prostanoid DP receptor; Ptgdr;
抗原和靶标
Expressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes.
- Q13258 PD2R_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
翻译修饰 - Q13258 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S254 | Phosphorylation | Uniprot | |
| S347 | Phosphorylation | Uniprot | |
| S352 | Phosphorylation | Uniprot | |
| T353 | Phosphorylation | Uniprot | |
| S357 | Phosphorylation | Uniprot | |
| S358 | Phosphorylation | Uniprot |
研究背景
Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity).
Cell membrane>Multi-pass membrane protein.
Expressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes.
Belongs to the G-protein coupled receptor 1 family.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
限制条款
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