CD69 Antibody - #AF5275

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产品: CD69 抗体
货号: AF5275
描述: Rabbit polyclonal antibody to CD69
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Bovine, Sheep, Dog
分子量: 23~40kD; 23kD(Calculated).
蛋白号: Q07108
RRID: AB_2837761

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Bovine(82%), Sheep(82%), Dog(90%)
克隆:
Polyclonal
特异性:
CD69 Antibody detects endogenous levels of total CD69.
RRID:
AB_2837761
引用格式: Affinity Biosciences Cat# AF5275, RRID:AB_2837761.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Activation inducer molecule (AIM/CD69); Activation inducer molecule; AIM; BL-AC/P26; BLAC/P26; C-type lectin domain family 2 member C; CD69; CD69 antigen (p60, early T-cell activation antigen); CD69 antigen; CD69 molecule; CD69_HUMAN; CLEC2C; EA1; Early activation antigen CD69; Early lymphocyte activation antigen; Early T cell activation antigen p60; Early T-cell activation antigen p60; GP32/28; Leu23; Leukocyte surface antigen Leu-23; MLR-3; MLR3; VEA; Very Early Activation Antigen;

抗原和靶标

免疫原:
Uniprot:

Q07108(CD69_HUMAN) >>Visit HPA database.

基因/基因ID:
CD69(969)
表达:
Q07108 CD69_HUMAN:

Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.

描述:
Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
序列:
MSSENCFVAENSSLHPESGQENDATSPHFSTRHEGSFQVPVLCAVMNVVFITILIIALIALSVGQYNCPGQYTFSMPSDSHVSSCSEDWVGYQRKCYFISTVKRSWTSAQNACSEHGATLAVIDSEKDMNFLKRYAGREEHWVGLKKEPGHPWKWSNGKEFNNWFNVTGSDKCVFLKNTEVSSMECEKNLYWICNKPYK

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Dog
90
Bovine
82
Sheep
82
Rabbit
73
Pig
0
Horse
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q07108 作为底物

Site PTM Type Enzyme
S13 Phosphorylation

研究背景

功能:

Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.

翻译修饰:

Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.

细胞定位:

Membrane>Single-pass type II membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.

亚基结构:

Homodimer; disulfide-linked.

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