GPR91 Antibody - #AF5316

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产品: GPR91 抗体
货号: AF5316
描述: Rabbit polyclonal antibody to GPR91
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit
分子量: 38 kDa; 39kD(Calculated).
蛋白号: Q9BXA5
RRID: AB_2837801

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(89%), Bovine(100%), Horse(89%), Sheep(100%), Rabbit(100%)
克隆:
Polyclonal
特异性:
GPR91 Antibody detects endogenous levels of total GPR91.
RRID:
AB_2837801
引用格式: Affinity Biosciences Cat# AF5316, RRID:AB_2837801.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

G protein coupled receptor 91; G-protein coupled receptor 91; GPR 91; P2Y purinoceptor 1; P2Y purinoceptor 1 like; P2Y purinoceptor 1-like; Purinergic Receptor P2U2; Succinate receptor 1; Succinate receptor; SUCN R1; SUCNR 1; SUCNR1; SUCR1_HUMAN;

抗原和靶标

免疫原:
Uniprot:

Q9BXA5(SUCR1_HUMAN) >>Visit HPA database.

基因/基因ID:
SUCNR1(56670)
表达:
Q9BXA5 SUCR1_HUMAN:

Expressed specifically in kidney.

描述:
FunctionReceptor for succinate.Tissue specificityExpressed specifically in kidney.Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
序列:
MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMNQLRHNFKSLTSFSRWAHELLLSFREK

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Bovine
100
Sheep
100
Rabbit
100
Pig
89
Horse
89
Dog
78
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

功能:

Receptor for succinate.

细胞定位:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed specifically in kidney.

蛋白家族:

Belongs to the G-protein coupled receptor 1 family.

研究领域

· Environmental Information Processing > Signal transduction > cAMP signaling pathway.   (View pathway)

文献引用

1). Succinate level is increased and succinate dehydrogenase exerts forward and reverse catalytic activities in lipopolysaccharides-stimulated cardiac tissue: The protective role of dimethyl malonate. European Journal of Pharmacology, 2023 (PubMed: 36549501) [IF=4.2]

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