产品: | GSTM2 抗体 |
货号: | DF6339 |
描述: | Rabbit polyclonal antibody to GSTM2 |
应用: | WB IHC |
反应: | Human, Mouse, Rat |
分子量: | 26kDa; 26kD(Calculated). |
蛋白号: | P28161 |
RRID: | AB_2838303 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF6339, RRID:AB_2838303.
展开/折叠
Glutathione S alkyltransferase M2; Glutathione S aralkyltransferase M2; Glutathione S aryltransferase M2; Glutathione S transferase 4; Glutathione S transferase M1; Glutathione S transferase M2 (muscle); Glutathione S transferase Mu 2 (muscle); Glutathione S transferase Mu 2; Glutathione S-transferase Mu 2; GST class mu 2; GST class-mu 2; GST muscle; GST4; GSTM; GSTM2; GSTM2-2; GSTM2_HUMAN; GTHMUS; MGC117303; S (hydroxyalkyl)glutathione lyase M2;
抗原和靶标
- P28161 GSTM2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
翻译修饰 - P28161 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y23 | Phosphorylation | Uniprot | |
T24 | Phosphorylation | Uniprot | |
S26 | Phosphorylation | Uniprot | |
K31 | Ubiquitination | Uniprot | |
K32 | Ubiquitination | Uniprot | |
R43 | Methylation | Uniprot | |
K50 | Ubiquitination | Uniprot | |
T67 | Phosphorylation | Uniprot | |
K69 | Ubiquitination | Uniprot | |
T71 | Phosphorylation | Uniprot | |
R78 | Methylation | Uniprot | |
K144 | Acetylation | Uniprot | |
S186 | Phosphorylation | Uniprot | |
K193 | Ubiquitination | Uniprot | |
K199 | Acetylation | Uniprot | |
K199 | Ubiquitination | Uniprot | |
S200 | Phosphorylation | Uniprot | |
S201 | Phosphorylation | Uniprot | |
K218 | Ubiquitination | Uniprot |
研究背景
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Cytoplasm.
Muscle.
Homodimer.
Belongs to the GST superfamily. Mu family.
研究领域
· Human Diseases > Drug resistance: Antineoplastic > Platinum drug resistance.
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma. (View pathway)
· Metabolism > Metabolism of other amino acids > Glutathione metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
限制条款
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