产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF6364, RRID:AB_2838328.
展开/折叠
CD236; CD236R; GE; GLPC; GLPC_HUMAN; Glycoconnectin; Glycophorin C (Gerbich blood group); Glycophorin D; Glycophorin-C; Glycophorin-D; Glycoprotein beta; GPC; GPD; Gypc; GYPD; MGC117309; MGC126191; MGC126192; PAS 2; PAS 2'; PAS-2''; Sialoglycoprotein D;
抗原和靶标
Glycophorin-C is expressed in erythrocytes. Glycophorin-D and IsoGPC are ubiquitously expressed.
- P04921 GLPC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAEPDPGMSGWPDGRMETSTPTIMDIVVIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEFAESADAALQGDPALQDAGDSSRKEYFI
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P04921 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S3 | O-Glycosylation | Uniprot | |
| T4 | O-Glycosylation | Uniprot | |
| S6 | O-Glycosylation | Uniprot | |
| N8 | N-Glycosylation | Uniprot | |
| S9 | O-Glycosylation | Uniprot | |
| T10 | O-Glycosylation | Uniprot | |
| S15 | O-Glycosylation | Uniprot | |
| S24 | O-Glycosylation | Uniprot | |
| S26 | O-Glycosylation | Uniprot | |
| T27 | O-Glycosylation | Uniprot | |
| T28 | O-Glycosylation | Uniprot | |
| T31 | O-Glycosylation | Uniprot | |
| T32 | O-Glycosylation | Uniprot | |
| T33 | O-Glycosylation | Uniprot | |
| S42 | O-Glycosylation | Uniprot | |
| K97 | Ubiquitination | Uniprot | |
| S104 | Phosphorylation | Uniprot | |
| S122 | Phosphorylation | Uniprot | |
| Y126 | Phosphorylation | Uniprot |
研究背景
This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells.
O-glycosylated with core 1 or possibly core 8 glycans.
Cell membrane>Single-pass type III membrane protein.
Note: Linked to the membrane via band 4.1.
Glycophorin-C is expressed in erythrocytes. Glycophorin-D and IsoGPC are ubiquitously expressed.
Belongs to the glycophorin-C family.
研究领域
· Human Diseases > Infectious diseases: Parasitic > Malaria.
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