产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF6394, RRID:AB_2838357.
展开/折叠
BPIFF; CETP; CETP_HUMAN; Cholesteryl ester transfer protein; Cholesteryl ester transfer protein plasma; HDLCQ10; Lipid transfer protein I;
抗原和靶标
- P11597 CETP_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSESVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS
翻译修饰 - P11597 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
N105 | N-Glycosylation | Uniprot | |
T113 | Phosphorylation | Uniprot | |
N257 | N-Glycosylation | Uniprot | |
S349 | Phosphorylation | Uniprot | |
N358 | N-Glycosylation | Uniprot | |
S400 | Phosphorylation | Uniprot | |
T407 | Phosphorylation | Uniprot |
研究背景
Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination.
Secreted>Extracellular space.
Note: Secreted in plasma.
Expressed by the liver and secreted in plasma.
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
研究领域
· Organismal Systems > Digestive system > Cholesterol metabolism.
限制条款
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