SCGB1A1 Antibody - #DF6581

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产品: SCGB1A1 抗体
货号: DF6581
描述: Rabbit polyclonal antibody to SCGB1A1
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
分子量: 10kDa; 10kD(Calculated).
蛋白号: P11684
RRID: AB_2838543

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
克隆:
Polyclonal
特异性:
SCGB1A1 Antibody detects endogenous levels of total SCGB1A1.
RRID:
AB_2838543
引用格式: Affinity Biosciences Cat# DF6581, RRID:AB_2838543.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Blastokinin; CC10; CC16; CCPBP; CCSP; Clara cell phospholipid binding protein; Clara cell phospholipid-binding protein; Clara cell specific 10 kD protein; Clara cells 10 kDa secretory protein; OTTHUMP00000236107; SCGB1A1; Secretoglobin family 1A member 1; Secretoglobin, family 1A, member 1 (uteroglobin); UG; UGB; UP-1; UP1; Urinary protein 1; Urine protein 1; UTER_HUMAN; Uteroglobin;

抗原和靶标

免疫原:
Uniprot:

P11684(UTER_HUMAN) >>Visit HPA database.

基因/基因ID:
SCGB1A1(7356)
表达:
P11684 UTER_HUMAN:

Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways).

描述:
This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010]
序列:
MKLAVTLTLVTLALCCSSASAEICPSFQRVIETLLMDTPSSYEAAMELFSPDQDMREAGAQLKKLVDTLPQKPRESIIKLMEKIAQSSLCN

翻译修饰 - P11684 作为底物

Site PTM Type Enzyme
T6 Phosphorylation

研究背景

功能:

Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.

细胞定位:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways).

亚基结构:

Antiparallel homodimer; disulfide-linked. Interaction with LMBR1L has been observed in but not in.

蛋白家族:

Belongs to the secretoglobin family.

文献引用

1). SCGB1A1 as a novel biomarker and promising therapeutic target for the management of HNSCC. Oncology letters, 2024 (PubMed: 39268163) [IF=2.5]

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