| 产品: | CD1D 抗体 |
| 货号: | DF6597 |
| 描述: | Rabbit polyclonal antibody to CD1D |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Bovine, Horse, Sheep, Rabbit |
| 分子量: | 38kDa; 38kD(Calculated). |
| 蛋白号: | P15813 |
| RRID: | AB_2838559 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF6597, RRID:AB_2838559.
展开/折叠
Antigen-presenting glycoprotein CD1d; CD1.1; CD1A; CD1d; CD1D antigen; CD1D antigen d polypeptide; CD1d molecule; CD1D_HUMAN; Cd1d1; differentiation antigen CD1 alpha 3; HMC class I antigen like glycoprotein CD1D; Ly 38; MGC34622; R3; R3G1; T cell surface glycoprotein CD1d; Thymocyte antigen CD1D;
抗原和靶标
Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
- P15813 CD1D_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGCLLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P15813 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N38 | N-Glycosylation | Uniprot | |
| N60 | N-Glycosylation | Uniprot | |
| S94 | Phosphorylation | Uniprot | |
| T322 | Phosphorylation | Uniprot | |
| S323 | Phosphorylation | Uniprot |
研究背景
Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
Cell membrane>Single-pass type I membrane protein. Basolateral cell membrane>Single-pass type I membrane protein. Endosome membrane>Single-pass type I membrane protein. Lysosome membrane>Single-pass type I membrane protein. Endoplasmic reticulum membrane>Single-pass type I membrane protein.
Note: Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.
Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
Heterodimer with B2M (beta-2-microglobulin). Interacts with MHC II.
研究领域
· Cellular Processes > Cellular community - eukaryotes > Tight junction. (View pathway)
· Human Diseases > Infectious diseases: Parasitic > Amoebiasis.
· Organismal Systems > Immune system > Hematopoietic cell lineage. (View pathway)
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