| 产品: | APOC2 抗体 |
| 货号: | DF6607 |
| 描述: | Rabbit polyclonal antibody to APOC2 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 分子量: | 11kDa; 11kD(Calculated). |
| 蛋白号: | P02655 |
| RRID: | AB_2838569 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF6607, RRID:AB_2838569.
展开/折叠
APC 2; APC2; Apo CII; APOC 2; ApoC II; APOC2; APOC2 protein; APOC2_HUMAN; ApoCII; Apolipoprotein C II; Apolipoprotein C II precursor; Apolipoprotein C2; ApolipoproteinCII; MGC75082;
抗原和靶标
- P02655 APOC2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGTRLLPALFLVLLVLGFEVQGTQQPQQDEMPSPTFLTQVKESLSSYWESAKTAAQNLYEKTYLPAVDEKLRDLYSKSTAAMSTYTGIFTDQVLSVLKGEE
翻译修饰 - P02655 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S43 | Phosphorylation | Uniprot | |
| Y47 | Phosphorylation | Uniprot | |
| S50 | Phosphorylation | Uniprot | |
| K98 | Ubiquitination | Uniprot |
研究背景
Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL.
Proapolipoprotein C-II is synthesized as a sialic acid containing glycoprotein which is subsequently desialylated prior to its proteolytic processing.
Proapolipoprotein C-II, the major form found in plasma undergoes proteolytic cleavage of its N-terminal hexapeptide to generate apolipoprotein C-II, which occurs as the minor form in plasma.
Secreted.
Liver and intestine.
Belongs to the apolipoprotein C2 family.
研究领域
· Organismal Systems > Digestive system > Cholesterol metabolism.
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