产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF6630, RRID:AB_2838592.
展开/折叠
CD362; Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; SDC2; SDC2_HUMAN; SYND2; Syndecan-2;
抗原和靶标
- P34741 SDC2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRRAWILLTLGLVACVSAESRAELTSDKDMYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P34741 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S41 | Phosphorylation | Uniprot | |
| T80 | O-Glycosylation | Uniprot | |
| S81 | O-Glycosylation | Uniprot | |
| T88 | O-Glycosylation | Uniprot | |
| T89 | O-Glycosylation | Uniprot | |
| T90 | O-Glycosylation | Uniprot | |
| T101 | O-Glycosylation | Uniprot | |
| T107 | O-Glycosylation | Uniprot | |
| S115 | Phosphorylation | Uniprot | |
| K174 | Ubiquitination | Uniprot | |
| Y179 | Phosphorylation | P12931 (SRC) | Uniprot |
| R184 | Methylation | Uniprot | |
| K185 | Ubiquitination | Uniprot | |
| S187 | Phosphorylation | P05129 (PRKCG) , P17252 (PRKCA) , P05771 (PRKCB) | Uniprot |
| S188 | Phosphorylation | P05771 (PRKCB) , P05129 (PRKCG) , P17252 (PRKCA) | Uniprot |
| Y191 | Phosphorylation | Uniprot | |
| K193 | Ubiquitination | Uniprot | |
| T196 | Phosphorylation | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| Y200 | Phosphorylation | Uniprot |
研究背景
Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).
O-glycosylated with core 1 or possibly core 8 glycans. Contains heparan sulfate.
Membrane>Single-pass type I membrane protein.
Interacts (via cytoplasmic domain) with SARM1 (By similarity). Forms a complex with SDCBP and PDCD6IP.
Belongs to the syndecan proteoglycan family.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
· Human Diseases > Infectious diseases: Parasitic > Malaria.
· Human Diseases > Cancers: Overview > Proteoglycans in cancer.
限制条款
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