IL2RG Antibody - #DF6642

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产品: IL2RG 抗体
货号: DF6642
描述: Rabbit polyclonal antibody to IL2RG
应用: WB IHC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Sheep, Dog
蛋白号: P31785
RRID: AB_2838604

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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实验方案
WB Handbook
IHC Protocol
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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
IL2RG Antibody detects endogenous levels of total IL2RG.
RRID:
AB_2838604
引用格式: Affinity Biosciences Cat# DF6642, RRID:AB_2838604.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CD132; CD132 antigen; CIDX; common cytokine receptor gamma chain; Cytokine receptor common subunit gamma; Gamma C; gamma(c); gammaC; IL-2 receptor subunit gamma; IL-2R gamma chain; IL-2R subunit gamma; IL-2RG; Il2rg; IL2RG_HUMAN; IMD4; interleukin 2 receptor, gamma; Interleukin-2 receptor subunit gamma; p64; SCIDX; SCIDX1;

抗原和靶标

免疫原:

A synthesized peptide derived from human IL2RG, corresponding to a region within N-terminal amino acids.

基因/基因ID:
IL2RG(3561)
描述:
The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010]

研究领域

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Jak-STAT signaling pathway.   (View pathway)

· Human Diseases > Infectious diseases: Viral > Measles.

· Human Diseases > Infectious diseases: Viral > HTLV-I infection.

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

· Human Diseases > Immune diseases > Inflammatory bowel disease (IBD).

· Human Diseases > Immune diseases > Primary immunodeficiency.

· Organismal Systems > Immune system > Th1 and Th2 cell differentiation.   (View pathway)

· Organismal Systems > Immune system > Th17 cell differentiation.   (View pathway)

文献引用

1). Activation of IL-2/IL-2R pathway by Hedyotis diffusa polysaccharide improves immunotherapy in colorectal cancer. International journal of biological macromolecules, 2025 (PubMed: 39954887) [IF=7.7]
2). Alleviating CB2-Dependent ER Stress and Mitochondrial Dysfunction Improves Chronic Cerebral Hypoperfusion-Induced Cognitive Impairment. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2024 (PubMed: 38214766) [IF=5.2]

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