IL1R2 Antibody - #DF6682

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产品: IL1R2 抗体
货号: DF6682
描述: Rabbit polyclonal antibody to IL1R2
应用: WB IHC IF/ICC
反应: Human, Mouse
预测: Horse, Dog
蛋白号: P27930
RRID: AB_2838644

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
IL1R2 Antibody detects endogenous levels of total IL1R2.
RRID:
AB_2838644
引用格式: Affinity Biosciences Cat# DF6682, RRID:AB_2838644.
偶联:
Unconjugated. 130
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

IL1 Receptor II; Antigen CDw121b; CD121; CD121 antigen-like family member B; CD121b; CD121B Antigen; CDw121b; IL 1 type II receptor; IL-1R-2; IL-1R-beta; IL-1R2; IL-1RT-2; IL-1RT2; IL1R Beta; Il1r-2; IL1R2; IL1R2_HUMAN; IL1R2c; IL1RB; Interleukin 1 receptor type II variant 3; Interleukin 1 receptor, beta, type II; Interleukin 1 receptor, type II; Interleukin-1 receptor beta; Interleukin-1 receptor type 2; Interleukin-1 receptor type II; MGC137383; MGC47725; OTTHUMP00000207969; p68; Type II interleukin-1 receptor, beta;

抗原和靶标

免疫原:

A synthesized peptide derived from human IL1R2, corresponding to a region within C-terminal amino acids.

基因/基因ID:
IL1R2(7850)
描述:
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.

文献引用

1). Single-cell RNA sequencing reveals the impaired epidermal differentiation and pathological microenvironment in diabetic foot ulcer. Burns & trauma, 2025 (PubMed: 40040959) [IF=6.3]
2). NLRP3 Inflammasome Activation of Mast Cells by Estrogen via the Nuclear-Initiated Signaling Pathway Contributes to the Development of Endometriosis. Frontiers in Immunology, 2021 (PubMed: 34630429) [IF=5.7]

Application: IHC    Species: Human    Sample: endometrial tissues

Figure 5 IL1R1 was over-expressed in ectopic endometrium. Representative photomicrographs of immunostaining with IL1R1 and IL1R2 in endometriotic lesions and eutopic endometrium from women with or without endometriosis. Scale bars = 100 μm. Immunostaining scores are represented as mean ± SEM. Statistical comparisons were carried out with Kruskal-Wallis test followed by Dunn’s multiple comparison test. *P < 0.05.

Application: IHC    Species: Human    Sample: endometrial tissues

Figure 5 IL1R1 was over-expressed in ectopic endometrium. Representative photomicrographs of immunostaining with IL1R1 and IL1R2 in endometriotic lesions and eutopic endometrium from women with or without endometriosis. Scale bars = 100 μm. Immunostaining scores are represented as mean ± SEM. Statistical comparisons were carried out with Kruskal-Wallis test followed by Dunn’s multiple comparison test. *P < 0.05.

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