产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF6686, RRID:AB_2838648.
展开/折叠
ABD-B; Abd-B, drosophila, homolog of; D6a9; Homeobox 1G; Homeobox A9; Homeobox protein Hox-1.7; Homeobox protein Hox-1G; Homeobox protein Hox-A9; Homeodomain protein HOXA9; Hox-1.7; Hox-1.7, mouse, homolog of; HOX1; Hox1.7; Hox1G; Hox1r5; Hoxa-9; Hoxa7; HOXA9; HOXA9/MSI2 fusion gene, included; HOXA9/NUP98 fusion gene, included; HXA9_HUMAN; MGC1934;
抗原和靶标
- P31269 HXA9_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATTGALGNYYVDSFLLGADAADELSVGRYAPGTLGQPPRQAATLAEHPDFSPCSFQSKATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P31269 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S120 | Phosphorylation | Uniprot | |
S126 | Phosphorylation | Uniprot | |
S184 | Phosphorylation | Uniprot | |
S205 | Phosphorylation | Uniprot | |
K209 | Ubiquitination | Uniprot | |
K215 | Ubiquitination | Uniprot |
研究背景
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation.
Methylated on Arg-140 by PRMT5; methylation is critical for E-selectin induction.
Nucleus.
Transiently interacts with PRMT5 in TNF-alpha stimulated endothelial cells.
Belongs to the Abd-B homeobox family.
研究领域
· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.
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