| 产品: | EPHX1 抗体 |
| 货号: | DF6799 |
| 描述: | Rabbit polyclonal antibody to EPHX1 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 53kDa; 53kD(Calculated). |
| 蛋白号: | P07099 |
| RRID: | AB_2838761 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF6799, RRID:AB_2838761.
展开/折叠
EPHX 1; EPHX; Ephx1; EPOX; Epoxide hydratase; Epoxide hydrolase 1; Epoxide hydrolase 1 microsomal (xenobiotic); Epoxide hydroxylase 1; Epoxide hydroxylase 1 microsomal (xenobiotic); HYEP_HUMAN; HYL1; MEH; Microsomal epoxide hydrolase;
抗原和靶标
- P07099 HYEP_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWLEILLTSVLGFAIYWFISRDKEETLPLEDGWWGPGTRSAAREDDSIRPFKVETSDEEIHDLHQRIDKFRFTPPLEDSCFHYGFNSNYLKKVISYWRNEFDWKKQVEILNRYPHFKTKIEGLDIHFIHVKPPQLPAGHTPKPLLMVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEVICPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVPSHVKGLHLNMALVLSNFSTLTLLLGQRFGRFLGLTERDVELLYPVKEKVFYSLMRESGYMHIQCTKPDTVGSALNDSPVGLAAYILEKFSTWTNTEFRYLEDGGLERKFSLDDLLTNVMLYWTTGTIISSQRFYKENLGQGWMTQKHERMKVYVPTGFSAFPFELLHTPEKWVRFKYPKLISYSYMVRGGHFAAFEEPELLAQDIRKFLSVLERQ
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P07099 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S47 | Phosphorylation | Uniprot | |
| K52 | Ubiquitination | Uniprot | |
| T55 | Phosphorylation | Uniprot | |
| S56 | Phosphorylation | Uniprot | |
| K91 | Ubiquitination | Uniprot | |
| K92 | Ubiquitination | Uniprot | |
| S95 | Phosphorylation | Uniprot | |
| K105 | Ubiquitination | Uniprot | |
| K117 | Methylation | Uniprot | |
| K119 | Methylation | Uniprot | |
| K131 | Acetylation | Uniprot | |
| K168 | Ubiquitination | Uniprot | |
| S173 | Phosphorylation | Uniprot | |
| K196 | Ubiquitination | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| T204 | Phosphorylation | Uniprot | |
| K210 | Acetylation | Uniprot | |
| Y283 | Phosphorylation | Uniprot | |
| K286 | Ubiquitination | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| Y291 | Phosphorylation | Uniprot | |
| S297 | Phosphorylation | Uniprot | |
| Y299 | Phosphorylation | Uniprot | |
| Y339 | Phosphorylation | Uniprot | |
| Y361 | Phosphorylation | Uniprot | |
| K386 | Acetylation | Uniprot | |
| K386 | Ubiquitination | Uniprot | |
| Y393 | Phosphorylation | Uniprot | |
| T408 | Phosphorylation | Uniprot | |
| S422 | Phosphorylation | Uniprot | |
| Y423 | Phosphorylation | Uniprot | |
| Y425 | Phosphorylation | Uniprot | |
| S450 | Phosphorylation | Uniprot |
研究背景
Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water (By similarity). May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids.
Microsome membrane>Single-pass type III membrane protein. Endoplasmic reticulum membrane>Single-pass type III membrane protein.
Found in liver.
Belongs to the peptidase S33 family.
研究领域
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.
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