| 产品: | LTA4H 抗体 |
| 货号: | DF6971 |
| 描述: | Rabbit polyclonal antibody to LTA4H |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 69kDa; 69kD(Calculated). |
| 蛋白号: | P09960 |
| RRID: | AB_2838927 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF6971, RRID:AB_2838927.
展开/折叠
FLJ17564; Leukotriene A(4) hydrolase; Leukotriene A-4 hydrolase; Leukotriene A4 hydrolase; LKHA4_HUMAN; LTA-4 hydrolase; LTA4; LTA4 hydrolase; LTA4H;
抗原和靶标
Isoform 1 and isoform 2 are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts.
- P09960 LKHA4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P09960 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S12 | Phosphorylation | Uniprot | |
| S15 | Phosphorylation | Uniprot | |
| K20 | Ubiquitination | Uniprot | |
| S27 | Phosphorylation | Uniprot | |
| T34 | Phosphorylation | Uniprot | |
| K58 | Acetylation | Uniprot | |
| K58 | Ubiquitination | Uniprot | |
| K64 | Ubiquitination | Uniprot | |
| K73 | Acetylation | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| K83 | Ubiquitination | Uniprot | |
| S90 | Phosphorylation | Uniprot | |
| S96 | Phosphorylation | Uniprot | |
| K127 | Ubiquitination | Uniprot | |
| C147 | S-Nitrosylation | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| S172 | Phosphorylation | Uniprot | |
| S186 | Phosphorylation | Uniprot | |
| K191 | Ubiquitination | Uniprot | |
| S212 | Phosphorylation | Uniprot | |
| K225 | Ubiquitination | Uniprot | |
| K230 | Ubiquitination | Uniprot | |
| S236 | Phosphorylation | Uniprot | |
| T238 | Phosphorylation | Uniprot | |
| K337 | Acetylation | Uniprot | |
| K337 | Ubiquitination | Uniprot | |
| K355 | Ubiquitination | Uniprot | |
| K365 | Ubiquitination | Uniprot | |
| K414 | Acetylation | Uniprot | |
| K414 | Ubiquitination | Uniprot | |
| S416 | Phosphorylation | Uniprot | |
| Y417 | Phosphorylation | Uniprot | |
| K418 | Acetylation | Uniprot | |
| K418 | Ubiquitination | Uniprot | |
| Y430 | Phosphorylation | Uniprot | |
| K434 | Acetylation | Uniprot | |
| K434 | Ubiquitination | Uniprot | |
| K480 | Acetylation | Uniprot | |
| K480 | Ubiquitination | Uniprot | |
| K493 | Ubiquitination | Uniprot | |
| K519 | Ubiquitination | Uniprot | |
| K557 | Ubiquitination | Uniprot | |
| K566 | Ubiquitination | Uniprot | |
| K573 | Acetylation | Uniprot | |
| K573 | Ubiquitination | Uniprot | |
| K580 | Ubiquitination | Uniprot | |
| K593 | Ubiquitination | Uniprot | |
| T600 | Phosphorylation | Uniprot | |
| K606 | Ubiquitination | Uniprot |
研究背景
Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity.
Phosphorylation at Ser-416 inhibits enzymatic activity.
Cytoplasm.
Isoform 1 and isoform 2 are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts.
Monomer.
Belongs to the peptidase M1 family.
研究领域
· Metabolism > Lipid metabolism > Arachidonic acid metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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