产品: LHB 抗体
货号: DF7140
描述: Rabbit polyclonal antibody to LHB
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
分子量: 15kD; 15kD(Calculated).
蛋白号: P01229
RRID: AB_2839094

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
克隆:
Polyclonal
特异性:
LHB Antibody detects endogenous levels of total LHB.
RRID:
AB_2839094
引用格式: Affinity Biosciences Cat# DF7140, RRID:AB_2839094.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CGB4; CHORIONIC GONADOTROPIN, BETA POLYPEPTIDE 4; hLHB; Interstitial cell stimulating hormone beta chain; Leutropin; LH-B; LHB; LSH beta; LSH-B; LSH-beta; LSHB; LSHB_HUMAN; Luteinizing hormone beta polypeptide; Luteinizing hormone subunit beta; Lutropin beta chain; Lutropin subunit beta;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
P01229 LSHB_HUMAN:

Pituitary gland.

描述:
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
序列:
MEMLQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPTMMRVLQAVLPPLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTSDCGGPKDHPLTCDHPQLSGLLFL

研究背景

功能:

Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.

细胞定位:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Pituitary gland.

亚基结构:

Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.

蛋白家族:

Belongs to the glycoprotein hormones subunit beta family.

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Organismal Systems > Endocrine system > Ovarian steroidogenesis.

· Organismal Systems > Endocrine system > Prolactin signaling pathway.   (View pathway)

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