产品: | GCLM 抗体 |
货号: | DF7268 |
描述: | Rabbit polyclonal antibody to GCLM |
应用: | WB IHC |
反应: | Human, Mouse, Rat, Pig |
预测: | Pig, Bovine, Rabbit |
分子量: | 30kDa; 31kD(Calculated). |
蛋白号: | P48507 |
RRID: | AB_2839207 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF7268, RRID:AB_2839207.
展开/折叠
Gamma ECS regulatory subunit; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; GCLM; GCS light chain; GLCLR; Glutamate cysteine ligase regulatory subunit; Glutamate--cysteine ligase modifier subunit; Glutamate--cysteine ligase regulatory subunit; GSC light chain; GSH0_HUMAN;
抗原和靶标
- P48507 GSH0_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQAHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P48507 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K9 | Sumoylation | Uniprot | |
K9 | Ubiquitination | Uniprot | |
T17 | Phosphorylation | Uniprot | |
K34 | Ubiquitination | Uniprot | |
C35 | S-Nitrosylation | Uniprot | |
K49 | Ubiquitination | Uniprot | |
C72 | S-Nitrosylation | Uniprot | |
K80 | Ubiquitination | Uniprot | |
K90 | Ubiquitination | Uniprot | |
K158 | Sumoylation | Uniprot | |
K158 | Ubiquitination | Uniprot | |
T164 | Phosphorylation | Uniprot | |
S165 | Phosphorylation | Uniprot | |
K169 | Ubiquitination | Uniprot | |
K205 | Sumoylation | Uniprot | |
K263 | Acetylation | Uniprot | |
K263 | Ubiquitination | Uniprot | |
Y265 | Phosphorylation | Uniprot | |
K270 | Ubiquitination | Uniprot |
研究背景
In all tissues examined. Highest levels in skeletal muscle.
Heterodimer of a catalytic heavy chain and a regulatory light chain.
Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
研究领域
· Cellular Processes > Cell growth and death > Ferroptosis. (View pathway)
· Metabolism > Amino acid metabolism > Cysteine and methionine metabolism.
· Metabolism > Metabolism of other amino acids > Glutathione metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
文献引用
Application: WB Species: Mice Sample: lung tissues
Application: WB Species: Mice Sample: kidney tissues
Application: WB Species: mouse Sample: liver
Application: WB Species: Rat Sample: liver tissues
Application: WB Species: Mouse Sample:
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