产品: | SGCE 抗体 |
货号: | DF7279 |
描述: | Rabbit polyclonal antibody to SGCE |
应用: | WB IHC |
反应: | Human, Mouse, Rat |
预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
分子量: | 50kDa; 50kD(Calculated). |
蛋白号: | O43556 |
RRID: | AB_2839218 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF7279, RRID:AB_2839218.
展开/折叠
dystonia 11, myoclonic; DYT11; Epsilon sarcoglycan; Epsilon SG; Epsilon-sarcoglycan; Epsilon-SG; ESG; sarcoglycan, epsilon; sgcE; SGCE_HUMAN;
抗原和靶标
- O43556 SGCE_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQNLPHQTQIPQQQTTGKWYP
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O43556 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T32 | Phosphorylation | Uniprot | |
T36 | Phosphorylation | Uniprot | |
Y38 | Phosphorylation | Uniprot | |
S39 | Phosphorylation | Uniprot | |
S46 | Phosphorylation | Uniprot | |
N200 | N-Glycosylation | Uniprot | |
S249 | Phosphorylation | Uniprot | |
T257 | Phosphorylation | Uniprot | |
K278 | Ubiquitination | Uniprot | |
K280 | Ubiquitination | Uniprot | |
K302 | Ubiquitination | Uniprot | |
Y337 | Phosphorylation | Uniprot | |
T353 | Phosphorylation | Uniprot | |
K369 | Ubiquitination | Uniprot | |
Y406 | Phosphorylation | Uniprot |
研究背景
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
N-glycosylated.
Ubiquitinated, leading to its degradation by the proteasome.
Cell membrane>Sarcolemma>Single-pass membrane protein. Cytoplasm>Cytoskeleton. Cell projection>Dendrite. Golgi apparatus.
Ubiquitous.
Belongs to the sarcoglycan alpha/epsilon family.
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