产品: | GP9/CD42a 抗体 |
货号: | DF7310 |
描述: | Rabbit polyclonal antibody to GP9/CD42a |
应用: | WB IHC |
反应: | Human, Rat |
预测: | Bovine, Rabbit, Dog |
分子量: | 37kDa; 19kD(Calculated). |
蛋白号: | P14770 |
RRID: | AB_2839248 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF7310, RRID:AB_2839248.
展开/折叠
CD42a; Glycoprotein 9; Glycoprotein IX; Glycoprotein IX (platelet); Glycoprotein IX precursor; GP IX; GP-IX; GP9; GPIX; GPIX_HUMAN; Platelet glycoprotein IX;
抗原和靶标
- P14770 GPIX_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAAHGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P14770 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T44 | Phosphorylation | Uniprot |
研究背景
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
Membrane>Single-pass type I membrane protein.
Two GP-Ib beta are disulfide-linked to one GP-Ib alpha. GP-IX is complexed with the GP-Ib heterodimer via a non covalent linkage.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > ECM-receptor interaction. (View pathway)
· Organismal Systems > Immune system > Platelet activation. (View pathway)
· Organismal Systems > Immune system > Hematopoietic cell lineage. (View pathway)
限制条款
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