产品: | CTSA 抗体 |
货号: | DF7381 |
描述: | Rabbit polyclonal antibody to CTSA |
应用: | WB IHC |
反应: | Human, Mouse, Rat |
预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
分子量: | 54kDa; 54kD(Calculated). |
蛋白号: | P10619 |
RRID: | AB_2839319 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF7381, RRID:AB_2839319.
展开/折叠
beta galactosidase 2; BETA GALACTOSIDASE PROTECTIVE PROTEIN; beta-galactosidase 2; beta-galactosidase protective protein; betagalactosidase 2; Carboxypeptidase C; Carboxypeptidase L; carboxypeptidase Y-like kininase; Cathepsin A; Ctsa; deamidase; EC 3.4.16.5; Glactosialidosis; GLB2; Goldberg Syndrome; GSL; lysosomal carboxypeptidase A; Lysosomal protective protein 20 kDa chain; Lysosomal protective protein; Lysosomal protective protein deficiency; NEURAMINIDASE BETA GALACTOSIDASE EXPRESSION; NGBE; Neuraminidase deficiency with beta-galactosidase deficiency; NGBE; OTTHUMP00000031778; OTTHUMP00000031781; PPCA; PPCA deficiency; PPGB; PPGB_HUMAN; Protective protein cathepsin A; Protective protein for beta galactosidase; Protective protein for beta-galactosidase; Protective protein/cathepsin A deficiency; urinary kininase;
抗原和靶标
- P10619 PPGB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MIRAAPPPLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P10619 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K55 | Methylation | Uniprot | |
N145 | N-Glycosylation | Uniprot | |
T295 | Phosphorylation | Uniprot | |
N333 | N-Glycosylation | Uniprot | |
K429 | Ubiquitination | Uniprot | |
Y430 | Phosphorylation | Uniprot | |
T469 | Phosphorylation | Uniprot | |
S472 | Phosphorylation | Uniprot |
研究背景
Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.
Lysosome.
Heterodimer of a 32 kDa chain and a 20 kDa chain; disulfide-linked.
Belongs to the peptidase S10 family.
研究领域
· Cellular Processes > Transport and catabolism > Lysosome. (View pathway)
· Organismal Systems > Endocrine system > Renin-angiotensin system. (View pathway)
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