Asparagine synthetase Antibody - #DF7398

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产品: Asparagine synthetase 抗体
货号: DF7398
描述: Rabbit polyclonal antibody to Asparagine synthetase
应用: WB IHC
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Rabbit, Dog, Chicken, Xenopus
分子量: 64kDa; 64kD(Calculated).
蛋白号: P08243
RRID: AB_2839336

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
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说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Zebrafish(100%), Bovine(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
克隆:
Polyclonal
特异性:
Asparagine synthetase Antibody detects endogenous levels of total Asparagine synthetase.
RRID:
AB_2839336
引用格式: Affinity Biosciences Cat# DF7398, RRID:AB_2839336.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

asnS; ASNS_HUMAN; ASNSD; Asparagine synthetase [glutamine-hydrolyzing]; Asparagine synthetase; Cell cycle control protein TS11; Glutamine dependent asparagine synthetase 3; Glutamine dependent asparagine synthetase; Glutamine hydrolyzing; Glutamine-dependent asparagine synthetase; OTTHUMP00000024510; OTTHUMP00000204938; OTTHUMP00000204939; OTTHUMP00000204940; OTTHUMP00000204941; OTTHUMP00000204942; TS11; TS11 cell cycle control protein;

抗原和靶标

免疫原:
Uniprot:

P08243(ASNS_HUMAN) >>Visit HPA database.

基因/基因ID:
ASNS(440)
描述:
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene.
序列:
MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQPIRVKKYPYLWLCYNGEIYNHKKMQQHFEFEYQTKVDGEIILHLYDKGGIEQTICMLDGVFAFVLLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVTLKHSATPFLKVEPFLPGHYEVLDLKPNGKVASVEMVKYHHCRDVPLHALYDNVEKLFPGFEIETVKNNLRILFNNAVKKRLMTDRRIGCLLSGGLDSSLVAATLLKQLKEAQVQYPLQTFAIGMEDSPDLLAARKVADHIGSEHYEVLFNSEEGIQALDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVVIFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLRELYLFDVLRADRTTAAHGLELRVPFLDHRFSSYYLSLPPEMRIPKNGIEKHLLRETFEDSNLIPKEILWRPKEAFSDGITSVKNSWFKILQEYVEHQVDDAMMANAAQKFPFNTPKTKEGYYYRQVFERHYPGRADWLSHYWMPKWINATDPSARTLTHYKSAVKA

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Bovine
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
100
Horse
0
Sheep
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P08243 作为底物

Site PTM Type Enzyme
K83 Ubiquitination
Y92 Phosphorylation
K132 Ubiquitination
K147 Methylation
K147 Ubiquitination
K162 Ubiquitination
K168 Ubiquitination
K176 Sumoylation
K176 Ubiquitination
Y185 Phosphorylation
K191 Acetylation
K191 Ubiquitination
K195 Ubiquitination
K203 Ubiquitination
K221 Ubiquitination
K232 Ubiquitination
K244 Ubiquitination
K245 Ubiquitination
S258 Phosphorylation
K272 Ubiquitination
K275 Ubiquitination
K350 Ubiquitination
K379 Ubiquitination
K385 Acetylation
K385 Ubiquitination
R407 Methylation
R417 Methylation
K440 Ubiquitination
K445 Ubiquitination
R449 Methylation
K460 Ubiquitination
K467 Methylation
K467 Ubiquitination
S471 Phosphorylation
S476 Phosphorylation
K478 Ubiquitination
K483 Ubiquitination
K504 Ubiquitination
K511 Ubiquitination
K513 Ubiquitination
R519 Methylation
R524 Methylation
K540 Ubiquitination
T545 Phosphorylation
S548 Phosphorylation
T551 Phosphorylation
Y555 Phosphorylation
K556 Methylation
K556 Ubiquitination
S557 Phosphorylation

研究背景

研究领域

· Metabolism > Amino acid metabolism > Alanine, aspartate and glutamate metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

文献引用

1). ATF4 inhibits tumor development and mediates p-GCN2/ASNS upregulation in colon cancer. Scientific reports, 2024 (PubMed: 38844625) [IF=4.6]

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