NDUFB6 Antibody - #DF2213

(2)  
产品: NDUFB6 抗体
货号: DF2213
描述: Rabbit polyclonal antibody to NDUFB6
应用: WB IF/ICC
反应: Human, Mouse, Rat
预测: Xenopus
分子量: 15 kDa; 15kD(Calculated).
蛋白号: O95139
RRID: AB_2839444

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Xenopus(82%)
克隆:
Polyclonal
特异性:
NDUFB6 Antibody detects endogenous levels of total NDUFB6.
RRID:
AB_2839444
引用格式: Affinity Biosciences Cat# DF2213, RRID:AB_2839444.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

B17; CI; CI B17; CI-B17; Complex I mitochondrial respiratory chain B17 subunit; Complex I-B17; Complex IB17; MGC13675; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6; NADH ubiquinone oxidoreductase B17 subunit; NADH ubiquinone oxidoreductase beta subunit 6; NADH-ubiquinone oxidoreductase B17 subunit; NDUB6_HUMAN; NDUFB6;

抗原和靶标

免疫原:
Uniprot:

O95139(NDUB6_HUMAN) >>Visit HPA database.

基因/基因ID:
NDUFB6(4712)
描述:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
序列:
MTGYTPDEKLRLQQLRELRRRWLKDQELSPREPVLPPQKMGPMEKFWNKFLENKSPWRKMVHGVYKKSIFVFTHVLVPVWIIHYYMKYHVSEKPYGIVEKKSRIFPGDTILETGEVIPPMKEFPDQHH

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Xenopus
82
Bovine
73
Dog
73
Rabbit
73
Sheep
64
Chicken
64
Pig
55
Horse
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - O95139 作为底物

Site PTM Type Enzyme
T2 Acetylation
T2 Phosphorylation
T5 Phosphorylation
K9 Ubiquitination
K24 Ubiquitination
S29 Phosphorylation
K49 Acetylation
K49 Ubiquitination
K54 Ubiquitination
S55 Phosphorylation
K66 Acetylation
K66 Ubiquitination
K67 Acetylation
K93 Ubiquitination
Y95 Phosphorylation
K100 Ubiquitination
T113 Phosphorylation

研究背景

功能:

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

细胞定位:

Mitochondrion inner membrane>Single-pass membrane protein>Matrix side.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Complex I is composed of 45 different subunits.

蛋白家族:

Belongs to the complex I NDUFB6 subunit family.

研究领域

· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).

· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.

· Human Diseases > Neurodegenerative diseases > Parkinson's disease.

· Human Diseases > Neurodegenerative diseases > Huntington's disease.

· Metabolism > Energy metabolism > Oxidative phosphorylation.

· Metabolism > Global and overview maps > Metabolic pathways.

· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling.   (View pathway)

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