| 产品: | ATP12A 抗体 |
| 货号: | DF2223 |
| 描述: | Rabbit polyclonal antibody to ATP12A |
| 应用: | WB IHC |
| 反应: | Human, Mouse |
| 预测: | Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 115kDa; 116kD(Calculated). |
| 蛋白号: | P54707 |
| RRID: | AB_2839454 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF2223, RRID:AB_2839454.
展开/折叠
ATP1AL1; ATPase H+/K+ transporting nongastric alpha polypeptide; ATPase Na+K+ transporting alpha-1 polypeptide-like; Hydrogen/potassium-exchanging ATPase 12A; Non-gastric H(+)/K(+) ATPase subunit alpha; Potassium-transporting ATPase alpha chain 2; Proton pump; Sodium/potassium ATPase alpha polypeptide-like;
抗原和靶标
Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level).
- P54707 AT12A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MHQKTPEIYSVELSGTKDIVKTDKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P54707 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T5 | Phosphorylation | Uniprot | |
| S10 | Phosphorylation | Uniprot | |
| K42 | Acetylation | Uniprot | |
| S94 | Phosphorylation | Uniprot | |
| T101 | Phosphorylation | Uniprot | |
| S169 | Phosphorylation | Uniprot | |
| T170 | Phosphorylation | Uniprot | |
| T362 | Phosphorylation | Uniprot | |
| K449 | Acetylation | Uniprot | |
| K459 | Acetylation | Uniprot | |
| K627 | Ubiquitination | Uniprot | |
| T632 | Phosphorylation | Uniprot | |
| T638 | Phosphorylation | Uniprot | |
| K640 | Ubiquitination | Uniprot | |
| K713 | Ubiquitination | Uniprot | |
| K788 | Ubiquitination | Uniprot | |
| K856 | Acetylation | Uniprot | |
| S985 | Phosphorylation | Uniprot | |
| Y1038 | Phosphorylation | Uniprot | |
| Y1039 | Phosphorylation | Uniprot |
研究背景
Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues.
Membrane>Multi-pass membrane protein.
Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level).
Composed of two subunits: alpha (catalytic) and beta.
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
研究领域
· Metabolism > Energy metabolism > Oxidative phosphorylation.
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