产品: SYF2 抗体
货号: DF2224
描述: Rabbit polyclonal antibody to SYF2
应用: WB
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 28kDa; 29kD(Calculated).
蛋白号: O95926
RRID: AB_2839455

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 50ul RMB¥ 1250 现货
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 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Zebrafish(100%), Bovine(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
克隆:
Polyclonal
特异性:
SYF2 Antibody detects endogenous levels of total SYF2.
RRID:
AB_2839455
引用格式: Affinity Biosciences Cat# DF2224, RRID:AB_2839455.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CBPIN; CCNDBP1 interactor; CCNDBP1-interactor; DKFZp564O2082; fSAP29; Functional spliceosome associated protein 29; GCIP interacting protein p29; GCIPIP; NTC31; P29; Pre mRNA splicing factor SYF2; Pre-mRNA-splicing factor syf2; syf2; SYF2 homolog; SYF2 homolog RNA splicing factor (S. cerevisiae); SYF2 homolog RNA splicing factor; SYF2_HUMAN;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
O95926 SYF2_HUMAN:

Abundantly expressed in the heart, skeletal muscle and kidney. Expressed at lower level other tissues.

描述:
May be involved in pre-mRNA splicing
序列:
MAAIAASEVLVDSAEEGSLAAAAELAAQKREQRLRKFRELHLMRNEARKLNHQEVVEEDKRLKLPANWEAKKARLEWELKEEEKKKECAARGEDYEKVKLLEISAEDAERWERKKKRKNPDLGFSDYAAAQLRQYHRLTKQIKPDMETYERLREKHGEEFFPTSNSLLHGTHVPSTEEIDRMVIDLEKQIEKRDKYSRRRPYNDDADIDYINERNAKFNKKAERFYGKYTAEIKQNLERGTAV

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
100
Horse
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - O95926 作为底物

Site PTM Type Enzyme
A2 Acetylation
S13 Phosphorylation
Y95 Phosphorylation
Y127 Phosphorylation
K143 Sumoylation
Y149 Phosphorylation
K155 Ubiquitination
Y196 Phosphorylation
Y210 Phosphorylation
Y226 Phosphorylation
K228 Acetylation
Y229 Phosphorylation
K234 Sumoylation
K234 Ubiquitination

研究背景

功能:

Involved in pre-mRNA splicing as component of the spliceosome.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Abundantly expressed in the heart, skeletal muscle and kidney. Expressed at lower level other tissues.

亚基结构:

Identified in the spliceosome C complex. Interacts with CCNDBP1.

蛋白家族:

Belongs to the SYF2 family.

研究领域

· Genetic Information Processing > Transcription > Spliceosome.

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