| 产品: | UBE2R2 抗体 |
| 货号: | DF2262 |
| 描述: | Rabbit polyclonal antibody to UBE2R2 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Monkey |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 27 kDa,17kDa; 27kD(Calculated). |
| 蛋白号: | Q712K3 |
| RRID: | AB_2839491 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF2262, RRID:AB_2839491.
展开/折叠
CDC34B; E2 CDC34B; E2 ubiquitin conjugating enzyme R2; FLJ20419; MGC10481; UB2R2; UB2R2_HUMAN; UBC3B; UBE2R2; Ubiquitin carrier protein R2; Ubiquitin conjugating enzyme E2 CDC34B; Ubiquitin conjugating enzyme E2 R2; Ubiquitin conjugating enzyme E2R 2; Ubiquitin conjugating enzyme UBC3B; Ubiquitin protein ligase R2; Ubiquitin-conjugating enzyme E2 R2; Ubiquitin-conjugating enzyme E2-CDC34B; Ubiquitin-protein ligase R2;
抗原和靶标
- Q712K3 UB2R2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAQQQMTSSQKALMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRDSKGKDKEYAEIIRKQVSATKAEAEKDGVKVPTTLAEYCIKTKVPSNDNSSDLLYDDLYDDDIDDEDEEEEDADCYDDDDSGNEES
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q712K3 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K11 | Ubiquitination | Uniprot | |
| K18 | Ubiquitination | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| K157 | Ubiquitination | Uniprot | |
| K159 | Ubiquitination | Uniprot | |
| R166 | Methylation | Uniprot | |
| K167 | Ubiquitination | Uniprot | |
| K173 | Ubiquitination | Uniprot | |
| K182 | Ubiquitination | Uniprot | |
| Y190 | Phosphorylation | Uniprot | |
| K193 | Ubiquitination | Uniprot | |
| K195 | Ubiquitination | Uniprot | |
| S202 | Phosphorylation | Uniprot | |
| Y207 | Phosphorylation | Uniprot | |
| S233 | Phosphorylation | P19784 (CSNK2A2) , P68400 (CSNK2A1) | Uniprot |
| S238 | Phosphorylation | Uniprot |
研究背景
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. May be involved in degradation of katenin.
When phosphorylated, interacts with beta-TrCP (BTRC).
Belongs to the ubiquitin-conjugating enzyme family.
研究领域
· Genetic Information Processing > Folding, sorting and degradation > Ubiquitin mediated proteolysis. (View pathway)
· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.
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