| 产品: | ATP6V1D 抗体 |
| 货号: | DF2263 |
| 描述: | Rabbit polyclonal antibody to ATP6V1D |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 28 kDa; 28kD(Calculated). |
| 蛋白号: | Q9Y5K8 |
| RRID: | AB_2839492 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF2263, RRID:AB_2839492.
展开/折叠
ATP6M; ATP6V1D; V-ATPase 28 kDa accessory protein; V-ATPase subunit D; V-type proton ATPase subunit D; Vacuolar ATP synthase subunit D; Vacuolar proton pump subunit D; VATD; VMA8;
抗原和靶标
- Q9Y5K8 VATD_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSGKDRIEIFPSRMAQTIMKARLKGAQTGRNLLKKKSDALTLRFRQILKKIIETKMLMGEVMREAAFSLAEAKFTAGDFSTTVIQNVNKAQVKIRAKKDNVAGVTLPVFEHYHEGTDSYELTGLARGGEQLAKLKRNYAKAVELLVELASLQTSFVTLDEAIKITNRRVNAIEHVIIPRIERTLAYIITELDEREREEFYRLKKIQEKKKILKEKSEKDLEQRRAAGEVLEPANLLAEEKDEDLLFE
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9Y5K8 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| K4 | Methylation | Uniprot | |
| R6 | Methylation | Uniprot | |
| S12 | Phosphorylation | Uniprot | |
| R13 | Methylation | Uniprot | |
| K20 | Acetylation | Uniprot | |
| K20 | Methylation | Uniprot | |
| K20 | Ubiquitination | Uniprot | |
| K24 | Ubiquitination | Uniprot | |
| K89 | Ubiquitination | Uniprot | |
| K98 | Ubiquitination | Uniprot | |
| T116 | Phosphorylation | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| Y119 | Phosphorylation | Uniprot | |
| T122 | Phosphorylation | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| Y200 | Phosphorylation | Uniprot | |
| S216 | Phosphorylation | Uniprot |
研究背景
Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium.
Membrane>Peripheral membrane protein>Cytoplasmic side.
Note: Localizes to centrosome and the base of the cilium.
V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d). Interacts with SNX10; may play a role in ciliogenesis.
Belongs to the V-ATPase D subunit family.
研究领域
· Cellular Processes > Transport and catabolism > Phagosome. (View pathway)
· Environmental Information Processing > Signal transduction > mTOR signaling pathway. (View pathway)
· Human Diseases > Infectious diseases: Bacterial > Vibrio cholerae infection.
· Human Diseases > Infectious diseases: Bacterial > Epithelial cell signaling in Helicobacter pylori infection.
· Human Diseases > Immune diseases > Rheumatoid arthritis.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Synaptic vesicle cycle.
· Organismal Systems > Excretory system > Collecting duct acid secretion.
限制条款
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