| 产品: | CUL7 抗体 |
| 货号: | DF2324 |
| 描述: | Rabbit polyclonal antibody to CUL7 |
| 应用: | WB |
| 反应: | Human, Mouse |
| 预测: | Horse, Sheep, Dog |
| 蛋白号: | Q14999 |
| RRID: | AB_2839548 |
产品描述
来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
反应:
Human, Mouse
克隆:
Polyclonal
特异性:
CUL7 Antibody detects endogenous levels of total CUL7.
RRID:
AB_2839548
引用格式: Affinity Biosciences Cat# DF2324, RRID:AB_2839548.
引用格式: Affinity Biosciences Cat# DF2324, RRID:AB_2839548.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:
展开/折叠
CUL-7; CUL7; CUL7_HUMAN; Cullin-7; dJ20C7.5; KIAA0076;
抗原和靶标
免疫原:
A synthesized peptide derived from human CUL7, corresponding to a region within C-terminal amino acids.
基因/基因ID:
描述:
Component of a probable SCF-like E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation (By similarity). Seems not to promote polyubiquitination and proteasomal degradation of TP53. In vitro, complexes of CUL7 with either CUL9 or FBXW8 or TP53 contain E3 ubiquitin-protein ligase activity.
研究领域
· Genetic Information Processing > Folding, sorting and degradation > Ubiquitin mediated proteolysis. (View pathway)
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