| 产品: | IL5RA 抗体 |
| 货号: | DF2529 |
| 描述: | Rabbit polyclonal antibody to IL5RA |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse |
| 预测: | Bovine, Horse, Sheep, Dog |
| 分子量: | 48 kDa; 48kD(Calculated). |
| 蛋白号: | Q01344 |
| RRID: | AB_2839735 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF2529, RRID:AB_2839735.
展开/折叠
CD125; CD125 antigen; CDw125; HSIL5R3; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL-5R-alpha; IL-5RA; IL5R; IL5RA; IL5RA_HUMAN; Interleukin 5 Receptor alpha; Interleukin 5 Receptor alpha chain; Interleukin 5 receptor alpha subunit; Interleukin 5 receptor subunit alpha; Interleukin 5 receptor type 3; Interleukin-5 receptor subunit alpha; MGC26560;
抗原和靶标
- Q01344 IL5RA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRNVNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVETLEDSVF
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q01344 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y65 | Phosphorylation | Uniprot |
研究背景
This is the receptor for interleukin-5. The alpha chain binds to IL5.
Membrane>Single-pass type I membrane protein.
Expressed on eosinophils and basophils.
Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors. Interacts with SDCBP.
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation.
Belongs to the type I cytokine receptor family. Type 5 subfamily.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
· Environmental Information Processing > Signal transduction > Jak-STAT signaling pathway. (View pathway)
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Organismal Systems > Immune system > Hematopoietic cell lineage. (View pathway)
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