| 产品: | PDCD1LG2 抗体 |
| 货号: | DF2561 |
| 描述: | Rabbit polyclonal antibody to PDCD1LG2 |
| 应用: | WB |
| 反应: | Human, Mouse |
| 预测: | Pig, Horse, Dog |
| 分子量: | 31 kDa; 31kD(Calculated). |
| 蛋白号: | Q9BQ51 |
| RRID: | AB_2839767 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF2561, RRID:AB_2839767.
展开/折叠
B7 dendritic cell molecule; B7-DC; B7DC; bA574F11.2; Btdc; Butyrophilin B7 DC; Butyrophilin B7-DC; Butyrophilin B7DC; CD 273; CD273; CD273 antigen; MGC142238; MGC142240; PD 1 ligand 2; PD L2; PD-1 ligand 2; PD-L2; PD1 ligand 2; PD1L2_HUMAN; PDCD 1 ligand 2; PDCD1 ligand 2; PDCD1L2; Pdcd1lg2; PDL 2; PDL2; Programmed cell death 1 ligand 2; Programmed death ligand 2;
抗原和靶标
Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
- Q9BQ51 PD1L2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIPFCIIAFIFIATVIALRKQLCQKLYSSKDTTKRPVTTTKREVNSAI
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9BQ51 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y114 | Phosphorylation | Uniprot | |
| T116 | Phosphorylation | Uniprot | |
| T128 | Phosphorylation | Uniprot | |
| S159 | Phosphorylation | Uniprot | |
| S165 | Phosphorylation | Uniprot | |
| S167 | Phosphorylation | Uniprot |
研究背景
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
Secreted.
Endomembrane system>Single-pass type I membrane protein.
Cell membrane>Single-pass type I membrane protein.
Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
Interacts with PDCD1.
Belongs to the immunoglobulin superfamily. BTN/MOG family.
研究领域
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
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