| 产品: | RASA2 抗体 |
| 货号: | DF2647 |
| 描述: | Rabbit polyclonal antibody to RASA2 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 96kDa; 97kD(Calculated). |
| 蛋白号: | Q15283 |
| RRID: | AB_2839853 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF2647, RRID:AB_2839853.
展开/折叠
GAP1m; GTPase activating protein of RAS; Ras GTPase activating protein 2; Ras GTPase-activating protein 2; RAS p21 protein activator 2; Rasa2; RASA2_HUMAN;
抗原和靶标
- Q15283 RASA2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAAAPAAAAASSEAPAASATAEPEAGDQDSREVRVLQSLRGKICEAKNLLPYLGPHKMRDCFCTINLDQEEVYRTQVVEKSLSPFFSEEFYFEIPRTFQYLSFYVYDKNVLQRDLRIGKVAIKKEDLCNHSGKETWFSLQPVDSNSEVQGKVHLELKLNELITENGTVCQQLVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEIFYFEVTRSSSYTRKSQFQVEEEDIEKLEIRIDLWNNGNLVQDVFLGEIKVPVNVLRTDSSHQAWYLLQPRDNGNKSSKTDDLGSLRLNICYTEDYVLPSEYYGPLKTLLLKSPDVQPISASAAYILSEICRDKNDAVLPLVRLLLHHDKLVPFATAVAELDLKDTQDANTIFRGNSLATRCLDEMMKIVGGHYLKVTLKPILDEICDSSKSCEIDPIKLKEGDNVENNKENLRYYVDKLFNTIVKSSMSCPTVMCDIFYSLRQMATQRFPNDPHVQYSAVSSFVFLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTLISKTIQTLGSWGSLSKSKSSFKETFMCEFFKMFQEEGYIIAVKKFLDEISSTETKESSGTSEPVHLKEGEMYKRAQGRTRIGKKNFKKRWFCLTSRELTYHKQPGSKDAIYTIPVKNILAVEKLEESSFNKKNMFQVIHTEKPLYVQANNCVEANEWIDVLCRVSRCNQNRLSFYHPSVYLNGNWLCCQETGENTLGCKPCTAGVPADIQIDIDEDRETERIYSLFTLSLLKLQKMEEACGTIAVYQGPQKEPDDYSNFVIEDSVTTFKTIQQIKSIIEKLDEPHEKYRKKRSSSAKYGSKENPIVGKAS
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q15283 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| K48 | Sumoylation | Uniprot | |
| K124 | Acetylation | Uniprot | |
| K134 | Ubiquitination | Uniprot | |
| K208 | Acetylation | Uniprot | |
| K209 | Acetylation | Uniprot | |
| K211 | Acetylation | Uniprot | |
| K213 | Acetylation | Uniprot | |
| K214 | Acetylation | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| Y226 | Phosphorylation | Uniprot | |
| K302 | Ubiquitination | Uniprot | |
| K357 | Ubiquitination | Uniprot | |
| K419 | Ubiquitination | Uniprot | |
| K423 | Ubiquitination | Uniprot | |
| K442 | Ubiquitination | Uniprot | |
| K462 | Ubiquitination | Uniprot | |
| T537 | Phosphorylation | Uniprot | |
| T544 | Phosphorylation | Uniprot | |
| S555 | Phosphorylation | Uniprot | |
| S557 | Phosphorylation | Uniprot | |
| S560 | Phosphorylation | Uniprot | |
| K584 | Ubiquitination | Uniprot | |
| K607 | Ubiquitination | Uniprot | |
| Y612 | Phosphorylation | Uniprot | |
| Y651 | Phosphorylation | Uniprot | |
| K656 | Ubiquitination | Uniprot | |
| T759 | Phosphorylation | Uniprot | |
| T782 | Phosphorylation | Uniprot | |
| Y786 | Phosphorylation | Uniprot | |
| Y796 | Phosphorylation | Uniprot | |
| K809 | Ubiquitination | Uniprot | |
| K815 | Ubiquitination | Uniprot |
研究背景
Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).
Cytoplasm. Cytoplasm>Perinuclear region.
研究领域
· Environmental Information Processing > Signal transduction > MAPK signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Ras signaling pathway. (View pathway)
· Human Diseases > Cancers: Overview > Viral carcinogenesis.
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