ELF1 Antibody - #AF0483

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产品: ELF1 抗体
货号: AF0483
描述: Rabbit polyclonal antibody to ELF1
应用: WB IF/ICC
反应: Human
预测: Horse
分子量: 67kDa; 67kD(Calculated).
蛋白号: P32519
RRID: AB_2834232

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Horse(80%)
克隆:
Polyclonal
特异性:
ELF1 Antibody detects endogenous levels of total ELF1.
RRID:
AB_2834232
引用格式: Affinity Biosciences Cat# AF0483, RRID:AB_2834232.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

E74 like factor 1; E74-like factor 1; ELF 1; ELF1; ELF1_HUMAN; Ets domain transcription factor; ETS related transcription factor Elf 1; ETS related transcription factor Elf1; ets-related transcription factor; ETS-related transcription factor Elf-1; mElf 1; p70; Sts1; TRANSCRIPTION FACTOR ELF 1;

抗原和靶标

免疫原:
Uniprot:

P32519(ELF1_HUMAN) >>Visit HPA database.

基因/基因ID:
ELF1(1997)
表达:
P32519 ELF1_HUMAN:

In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.

描述:
Elf-1 Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. Belongs to the ETS family. Binds to the underphosphorylated form of RB. May interact with other transcription factors in order to regulate specific genes.
序列:
MAAVVQQNDLVFEFASNVMEDERQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDDDDDDITLTVEASCHDGDETIETIEAAEALLNMDSPGPMLDEKRINNNIFSSPEDDMVVAPVTHVSVTLDGIPEVMETQQVQEKYADSPGASSPEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLIYINDEDPSSSIESSDPSLSSSATSNRNQTSRSRVSSSPGVKGGATTVLKPGNSKAAKPKDPVEVAQPSEVLRTVQPTQSPYPTQLFRTVHVVQPVQAVPEGEAARTSTMQDETLNSSVQSIRTIQAPTQVPVVVSPRNQQLHTVTLQTVPLTTVIASTDPSAGTGSQKFILQAIPSSQPMTVLKENVMLQSQKAGSPPSIVLGPAQVQQVLTSNVQTICNGTVSVASSPSFSATAPVVTFSPRSSQLVAHPPGTVITSVIKTQETKTLTQEVEKKESEDHLKENTEKTEQQPQPYVMVVSSSNGFTSQVAMKQNELLEPNSF

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Horse
80
Pig
0
Bovine
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P32519 作为底物

Site PTM Type Enzyme
S110 Phosphorylation
Y160 Phosphorylation
S163 Phosphorylation
S167 Phosphorylation
S168 Phosphorylation
T180 Phosphorylation
S187 Phosphorylation
T190 Phosphorylation
T191 Phosphorylation
S195 Phosphorylation
K197 Ubiquitination
K226 Ubiquitination
K229 Ubiquitination
T231 Phosphorylation
K239 Ubiquitination
K244 Ubiquitination
K256 Ubiquitination
Y261 Phosphorylation
R269 Methylation
Y271 Phosphorylation
Y272 Phosphorylation
K279 Sumoylation
K279 Ubiquitination
K290 Ubiquitination
S332 Phosphorylation
S333 Phosphorylation
S334 Phosphorylation
K346 Acetylation
S350 Phosphorylation
S376 Phosphorylation
S432 Phosphorylation
S474 Phosphorylation
K481 Ubiquitination
T559 Phosphorylation
T566 Phosphorylation
K571 Ubiquitination
S618 Phosphorylation

研究背景

功能:

Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.

亚基结构:

Binds to the underphosphorylated form of RB. May interact with other transcription factors in order to regulate specific genes. Interacts with RUNX1.

蛋白家族:

Belongs to the ETS family.

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