Phospho-KIF1C (Ser1092) Antibody - #AF8091

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产品: 磷酸化 KIF1C (Ser1092) 抗体
货号: AF8091
描述: Rabbit polyclonal antibody to Phospho-KIF1C (Ser1092)
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 120~150kD; 123kD(Calculated).
蛋白号: O43896
RRID: AB_2840154

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   规格 价格 库存
 100ul RMB¥ 2800 现货
 200ul RMB¥ 3800 现货

货期: 当天发货

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MS Report
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WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
克隆:
Polyclonal
特异性:
Phospho-KIF1C (Ser1092) Antibody detects endogenous levels of KIF1C only when phosphorylated at Ser1092.
RRID:
AB_2840154
引用格式: Affinity Biosciences Cat# AF8091, RRID:AB_2840154.
偶联:
Unconjugated.
纯化:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Kif1c; KIF1C_HUMAN; Kinesin family member 1C; Kinesin-like protein KIF1C; LTXS1;

抗原和靶标

免疫原:
Uniprot:

O43896(KIF1C_HUMAN) >>Visit HPA database.

基因/基因ID:
KIF1C(10749)
表达:
O43896 KIF1C_HUMAN:

Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.

序列:
MAGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVPQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSEKVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIINEDPNARLIRELQEEVARLRELLMAQGLSASALEGLKTEEGSVRGALPAVSSPPAPVSPSSPTTHNGELEPSFSPNTESQIGPEEAMERLQETEKIIAELNETWEEKLRKTEALRMEREALLAEMGVAVREDGGTVGVFSPKKTPHLVNLNEDPLMSECLLYHIKDGVTRVGQVDMDIKLTGQFIREQHCLFRSIPQPDGEVVVTLEPCEGAETYVNGKLVTEPLVLKSGNRIVMGKNHVFRFNHPEQARLERERGVPPPPGPPSEPVDWNFAQKELLEQQGIDIKLEMEKRLQDLENQYRKEKEEADLLLEQQRLYADSDSGDDSDKRSCEESWRLISSLREQLPPTTVQTIVKRCGLPSSGKRRAPRRVYQIPQRRRLQGKDPRWATMADLKMQAVKEICYEVALADFRHGRAEIEALAALKMRELCRTYGKPDGPGDAWRAVARDVWDTVGEEEGGGAGSGGGSEEGARGAEVEDLRAHIDKLTGILQEVKLQNSSKDRELQALRDRMLRMERVIPLAQDHEDENEEGGEVPWAPPEGSEAAEEAAPSDRMPSARPPSPPLSSWERVSRLMEEDPAFRRGRLRWLKQEQLRLQGLQGSGGRGGGLRRPPARFVPPHDCKLRFPFKSNPQHRESWPGMGSGEAPTPLQPPEEVTPHPATPARRPPSPRRSHHPRRNSLDGGGRSRGAGSAQPEPQHFQPKKHNSYPQPPQPYPAQRPPGPRYPPYTTPPRMRRQRSAPDLKESGAAV

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - O43896 作为底物

Site PTM Type Enzyme
S162 Phosphorylation
T222 Phosphorylation
K243 Ubiquitination
S257 Phosphorylation
S258 Phosphorylation
K266 Ubiquitination
S274 Phosphorylation
T276 Phosphorylation
T277 Phosphorylation
S295 Phosphorylation
S326 Phosphorylation
Y332 Phosphorylation
S385 Phosphorylation
S412 Phosphorylation
T489 Phosphorylation
S494 Phosphorylation
K658 Ubiquitination
Y671 Phosphorylation
S674 Phosphorylation
S676 Phosphorylation
S680 Phosphorylation
T702 Phosphorylation
T703 Phosphorylation
Y726 Phosphorylation
K788 Ubiquitination
S817 Phosphorylation
K839 Ubiquitination
K848 Ubiquitination
S915 Phosphorylation
S919 Phosphorylation
R948 Methylation
S955 Phosphorylation
R958 Methylation
R963 Methylation
S996 Phosphorylation
S1022 Phosphorylation
S1033 Phosphorylation
R1041 Methylation
K1057 Methylation
R1072 Methylation
R1077 Methylation
Y1078 Phosphorylation
Y1081 Phosphorylation
T1082 Phosphorylation
T1083 Phosphorylation
S1092 Phosphorylation P68400 (CSNK2A1) , P19784 (CSNK2A2)

研究背景

功能:

Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.

翻译修饰:

Phosphorylated on tyrosine residues.

细胞定位:

Cytoplasm>Cytoskeleton.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.

亚基结构:

Monomer. Interacts with BICD2.

蛋白家族:

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily.

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