Phospho-IKK epsilon (Ser172) Antibody - #AF8156

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产品: 磷酸化 IKK epsilon (Ser172) 抗体
货号: AF8156
描述: Rabbit polyclonal antibody to Phospho-IKK epsilon (Ser172)
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus
蛋白号: Q14164
RRID: AB_2840218

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   规格 价格 库存
 100ul RMB¥ 2800 现货
 200ul RMB¥ 3800 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
Phospho-IKK epsilon (Ser172) Antibody detects endogenous levels of IKK epsilon only when phosphorylated at Ser172.
RRID:
AB_2840218
引用格式: Affinity Biosciences Cat# AF8156, RRID:AB_2840218.
偶联:
Unconjugated.
纯化:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

I kappa B kinase epsilon; I-kappa-B kinase epsilon; IkBKE; IKK related kinase epsilon; IKK-E; IKK-epsilon; IKK-i; IKKE; IKKE_HUMAN; IKKepsilon; IKKI; Inducible I kappa B kinase; Inducible I kappa-B kinase; Inducible IkappaB kinase; Inhibitor of kappa light polypeptide gene enhancer in B cells kinase epsilon; Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, epsilon; Inhibitor of nuclear factor kappa-B kinase subunit epsilon; KIAA0151; MGC125294; MGC125295; MGC125297;

抗原和靶标

免疫原:

A synthesized peptide derived from human IKK-ε around the phosphorylation site of Ser172.

基因/基因ID:
IKBKE(9641)

研究领域

· Human Diseases > Infectious diseases: Viral > Hepatitis C.

· Human Diseases > Infectious diseases: Viral > Hepatitis B.

· Human Diseases > Infectious diseases: Viral > Measles.

· Human Diseases > Infectious diseases: Viral > Influenza A.

· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.

· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.

· Organismal Systems > Immune system > Toll-like receptor signaling pathway.   (View pathway)

· Organismal Systems > Immune system > NOD-like receptor signaling pathway.   (View pathway)

· Organismal Systems > Immune system > RIG-I-like receptor signaling pathway.   (View pathway)

· Organismal Systems > Immune system > Cytosolic DNA-sensing pathway.   (View pathway)

· Organismal Systems > Immune system > IL-17 signaling pathway.   (View pathway)

文献引用

1). The PICK1/TLR4 complex on microglia is involved in the regulation of LPS-induced sepsis-associated encephalopathy. International Immunopharmacology, 2021 (PubMed: 34500285) [IF=4.8]

Application: WB    Species: Mouse    Sample:

Fig. 2. After LPS stimulation, the combination of TLR4 and IBa1 increases, and the TLR4 signaling pathway is activated. (A) Representative images show cellular localization of TLR4 in microglia in the hippocampus, Scale bar, 100 μm.Look at the red box and zoom in and you can see that: blue staining represents DAPI, red staining represents IBa1, green staining represents TLR4, Scale bar, 5 μm (B) Representative images of Western blots of LPS-treated mice of Hippocampus. (C–H) Quantitative analyses of IBa1, TLR4, TRAF3, phospho-TBK1, phospho-IKKε, and phospho-IRF3.The data are expressed as the mean ± standard error of the mean

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