| 产品: | 磷酸化 BORA (Ser497) 抗体 |
| 货号: | AF8249 |
| 描述: | Rabbit polyclonal antibody to Phospho-BORA (Ser497) |
| 应用: | WB |
| 反应: | Human, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus |
| 分子量: | 61kDa; 61kD(Calculated). |
| 蛋白号: | Q6PGQ7 |
| RRID: | AB_2840311 |
产品描述
来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
反应:
Human,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(89%), Chicken(89%), Xenopus(89%)
克隆:
Polyclonal
特异性:
Phospho-BORA (Ser497) Antibody detects endogenous levels of BORA only when phosphorylated at Ser497.
RRID:
AB_2840311
引用格式: Affinity Biosciences Cat# AF8249, RRID:AB_2840311.
引用格式: Affinity Biosciences Cat# AF8249, RRID:AB_2840311.
偶联:
Unconjugated.
纯化:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:
展开/折叠
Aurora borealis; bora; bora, aurora kinase A activator; BORA_HUMAN; C13orf34; Chromosome 13 open reading frame 34; FLJ22624; HsBora; Protein aurora borealis; RP11-342J4.2;
抗原和靶标
免疫原:
Uniprot:
基因/基因ID:
序列:
- Q6PGQ7 BORA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGDVKESKMQITPETPGRIPVLNPFESPSDYSNLHEQTLASPSVFKSTKLPTPGKFRWSIDQLAVINPVEIDPEDIHRQALYLSHSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHEGKQLSQCHSSKCTNINSDSPVGKKLTIHSEKSDAACQTLLSLPVDFNLENILGDYFRADEFADQSPGNLSSSSLRRKLFLDGNGSISDSLPSASPGSPHSGVQTSLEMFYSIDLSPVKCRSPLQTPSSGQFSSSPIQASAKKYSLGSITSPSPISSPTFSPIEFQIGETPLSEQRKFTVHSPDASSGTNSNGITNPCIRSPYIDGCSPIKNWSPMRLQMYSGGTQYRTSVIQIPFTLETQGEDEEDKENIPSTDVSSPAMDAAGIHLRQFSNEASTHGTHLVVTAMSVTQNQSSASEKELALLQDVEREKDNNTVDMVDPIEIADETTWIKEPVDNGSLPMTDFVSGIAFSIENSHMCMSPLAESSVIPCESSNIQMDSGYNTQNCGSNIMDTVGAESYCKESDAQTCEVESKSQAFNMKQDHTTQRCWMKTASPFQCSSP
种属预测
种属预测:
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Xenopus
89
Chicken
89
Rabbit
89
Zebrafish
78
Dog
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q6PGQ7 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y31 | Phosphorylation | Uniprot | |
| T38 | Phosphorylation | Uniprot | |
| S41 | Phosphorylation | Uniprot | |
| K46 | Ubiquitination | Uniprot | |
| T52 | Phosphorylation | Uniprot | |
| Y82 | Phosphorylation | Uniprot | |
| K95 | Acetylation | Uniprot | |
| K98 | Acetylation | Uniprot | |
| K106 | Acetylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| S112 | Phosphorylation | Uniprot | |
| K120 | Ubiquitination | Uniprot | |
| S135 | Phosphorylation | Uniprot | |
| S137 | Phosphorylation | Uniprot | |
| K142 | Ubiquitination | Uniprot | |
| S183 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| S189 | Phosphorylation | Uniprot | |
| S190 | Phosphorylation | Uniprot | |
| S191 | Phosphorylation | Uniprot | |
| S239 | Phosphorylation | Uniprot | |
| S252 | Phosphorylation | P06493 (CDK1) | Uniprot |
| S270 | Phosphorylation | Uniprot | |
| S274 | Phosphorylation | P49841 (GSK3B) | Uniprot |
| S278 | Phosphorylation | P49841 (GSK3B) | Uniprot |
| T296 | Phosphorylation | Uniprot | |
| S299 | Phosphorylation | Uniprot | |
| S303 | Phosphorylation | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| S325 | Phosphorylation | P50750 (CDK9) | Uniprot |
| S331 | Phosphorylation | Uniprot | |
| S339 | Phosphorylation | Uniprot | |
| T432 | Phosphorylation | Uniprot | |
| T445 | Phosphorylation | Uniprot | |
| T446 | Phosphorylation | Uniprot | |
| S497 | Phosphorylation | P53350 (PLK1) | Uniprot |
| T501 | Phosphorylation | Q13535 (ATR) , P53350 (PLK1) | Uniprot |
| K531 | Ubiquitination | Uniprot | |
| K538 | Ubiquitination | Uniprot | |
| S552 | Phosphorylation | Uniprot | |
| S558 | Phosphorylation | Uniprot |
研究背景
功能:
Required for the activation of AURKA at the onset of mitosis.
翻译修饰:
Phosphorylated by AURKA.
亚基结构:
Interacts with AURKA.
蛋白家族:
Belongs to the BORA family.
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