| 产品: | 磷酸化 CBX1 / HP1 beta (Thr51) 抗体 |
| 货号: | AF8483 |
| 描述: | Rabbit polyclonal antibody to Phospho-CBX1 / HP1 beta (Thr51) |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 25 kDa; 21kD(Calculated). |
| 蛋白号: | P83916 |
| RRID: | AB_2840537 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF8483, RRID:AB_2840537.
展开/折叠
CBX 1; CBX; Cbx1; CBX1_HUMAN; Chromobox 1; Chromobox homolog 1 (HP1 beta homolog Drosophila ); chromobox homolog 1; Chromobox protein homolog 1; Drosophila HP1 beta; Heterochromatin protein 1 beta; Heterochromatin protein 1 homolog beta; Heterochromatin protein p25; heterochromatin protein p25 beta; HP1 beta; HP1 beta homolog; HP1 beta homolog Drosophila; HP1, Drosophila. homolog of, beta; HP1beta; HP1Hs beta; HP1Hsbeta; Human heterochromatin protein p25 mRNA complete cds; M31; MOD 1; MOD1; Modifier 1 protein; p25beta;
抗原和靶标
A synthesized peptide derived from human HP1-β around the phosphorylation site of Thr51.
- P83916 CBX1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Not phosphorylated.
Ubiquitinated.
Nucleus.
Note: Unassociated with chromosomes during mitosis.
Expressed in all adult and embryonic tissues.
限制条款
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