Phospho-Thymidine Kinase 1/TK1 (Ser13) Antibody - #AF3068
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF3068, RRID:AB_2834493.
展开/折叠
cytosolic; KITH_HUMAN; Thymidine kinase 1; Thymidine kinase 1 soluble; Thymidine kinase 1 soluble isoform; Thymidine kinase; Thymidine kinase cytosolic; TK 1; TK 2; TK1; Tk1a; Tk1b; TK2;
抗原和靶标
- P04183 KITH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVIVAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADKYHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P04183 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| T8 | Phosphorylation | Uniprot | |
| S13 | Phosphorylation | P06493 (CDK1) , P24941 (CDK2) | Uniprot |
| S15 | Phosphorylation | Uniprot | |
| K16 | Ubiquitination | Uniprot | |
| S30 | Phosphorylation | Uniprot | |
| K32 | Acetylation | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| K49 | Ubiquitination | Uniprot | |
| Y55 | Phosphorylation | Uniprot | |
| S62 | Phosphorylation | Uniprot | |
| R70 | Methylation | Uniprot | |
| K131 | Ubiquitination | Uniprot | |
| K164 | Acetylation | Uniprot | |
| K170 | Ubiquitination | Uniprot | |
| K180 | Ubiquitination | Uniprot | |
| Y181 | Phosphorylation | Uniprot | |
| S183 | Phosphorylation | Uniprot | |
| K192 | Ubiquitination | Uniprot | |
| K203 | Ubiquitination | Uniprot | |
| K211 | Ubiquitination | Uniprot | |
| K220 | Acetylation | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| C230 | S-Nitrosylation | Uniprot | |
| S231 | Phosphorylation | Uniprot |
研究背景
Phosphorylated on Ser-13 in mitosis.
Cytoplasm.
Homotetramer.
Belongs to the thymidine kinase family.
研究领域
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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