产品: 磷酸化 FABP7 (Thr117) 抗体
货号: AF7034
描述: Rabbit polyclonal antibody to Phospho-FABP7 (Thr117)
应用: WB IHC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus
分子量: 15kDa; 15kD(Calculated).
蛋白号: O15540
RRID: AB_2843474

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   规格 价格 库存
 100ul RMB¥ 2800 现货
 200ul RMB¥ 3800 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(88%), Horse(88%), Sheep(100%), Dog(100%), Chicken(100%), Xenopus(88%)
克隆:
Polyclonal
特异性:
Phospho-FABP7 (Thr117) Antibody detects endogenous levels of FABP7 only when phosphorylated at Thr117.
RRID:
AB_2843474
引用格式: Affinity Biosciences Cat# AF7034, RRID:AB_2843474.
偶联:
Unconjugated.
纯化:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

B FABP; B-FABP; BFABP; BLBP; Brain lipid binding protein; Brain lipid-binding protein; Brain-type fatty acid-binding protein; DKFZp547J2313; FABP 7; FABP7; FABP7_HUMAN; FABPB; Fatty Acid Binding Protein 7; Fatty acid binding protein 7 brain; Fatty acid binding protein brain; Fatty acid-binding protein 7; Fatty acid-binding protein, brain; Mammary derived growth inhibitor related; Mammary-derived growth inhibitor related; MRG; OTTHUMP00000017119;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
O15540 FABP7_HUMAN:

Expressed in brain and other neural tissues.

序列:
MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKNTEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTLTFGDVVAVRHYEKA

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
100
Sheep
100
Dog
100
Chicken
100
Horse
88
Bovine
88
Xenopus
88
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - O15540 作为底物

Site PTM Type Enzyme
T54 Phosphorylation
T57 Phosphorylation
T61 Phosphorylation
T117 Phosphorylation
T119 Phosphorylation
Y129 Phosphorylation

研究背景

功能:

B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity).

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in brain and other neural tissues.

蛋白家族:

Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

研究领域

· Organismal Systems > Endocrine system > PPAR signaling pathway.

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