Phospho-SLC16A1 (Ser213) Antibody - #AF7044
产品: | 磷酸化 SLC16A1 (Ser213) 抗体 |
货号: | AF7044 |
描述: | Rabbit polyclonal antibody to Phospho-SLC16A1 (Ser213) |
应用: | WB IHC |
反应: | Human, Mouse, Rat |
分子量: | 54kDa; 54kD(Calculated). |
蛋白号: | P53985 |
RRID: | AB_2843484 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF7044, RRID:AB_2843484.
展开/折叠
FLJ36745; HHF7; MCT 1; MCT; MGC44475; Monocarboxylate transporter 1; Monocarboxylate transporter; Monocarboxylate transporter isoform 1; Monocarboxylic acid transporter 1; MOT1_HUMAN; Slc16a1; SLC16A1 protein; Solute carrier family 16 (monocarboxylic acid transporters) member 1; Solute carrier family 16 member 1 (monocarboxylic acid transporter 1); Solute carrier family 16 member 1;
抗原和靶标
Detected in heart and in blood lymphocytes and monocytes (at protein level). Widely expressed.
- P53985 MOT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQKDTDGGPKEEESPV
翻译修饰 - P53985 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S33 | Phosphorylation | Uniprot | |
Y34 | Phosphorylation | Uniprot | |
K211 | Ubiquitination | Uniprot | |
S213 | Phosphorylation | Uniprot | |
K216 | Ubiquitination | Uniprot | |
K224 | Ubiquitination | Uniprot | |
K239 | Ubiquitination | Uniprot | |
S244 | Phosphorylation | Uniprot | |
T248 | Phosphorylation | Uniprot | |
K459 | Ubiquitination | Uniprot | |
S461 | Phosphorylation | Uniprot | |
K462 | Ubiquitination | Uniprot | |
T466 | Phosphorylation | Uniprot | |
S467 | Phosphorylation | Uniprot | |
K473 | Ubiquitination | Uniprot | |
K479 | Ubiquitination | Uniprot | |
S483 | Phosphorylation | Uniprot | |
K487 | Ubiquitination | Uniprot | |
T489 | Phosphorylation | Uniprot | |
K494 | Methylation | Uniprot | |
K494 | Ubiquitination | Uniprot | |
S498 | Phosphorylation | Uniprot |
研究背景
Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.
Cell membrane>Multi-pass membrane protein.
Detected in heart and in blood lymphocytes and monocytes (at protein level). Widely expressed.
Interacts with EMB. Interaction with either BSG or EMB is required for expression at the cell membrane (By similarity). Interacts with BSG; this is required for expression at the cell membrane.
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
文献引用
Application: WB Species: Rabbit Sample:
限制条款
产品的规格、报价、验证数据请以官网为准,官网链接:www.affbiotech.com | www.affbiotech.cn(简体中文)| www.affbiotech.jp(日本語)产品的数据信息为Affinity所有,未经授权不得收集Affinity官网数据或资料用于商业用途,对抄袭产品数据的行为我们将保留诉诸法律的权利。
产品相关数据会因产品批次、产品检测情况随时调整,如您已订购该产品,请以订购时随货说明书为准,否则请以官网内容为准,官网内容有改动时恕不另行通知。
Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时,请您在Affinity官方渠道提交售后申请。产品仅供科学研究使用。不用于诊断和治疗。
产品未经授权不得转售。
Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.