Phospho-FABP1 (Ser11) Antibody - #AF7055

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产品: 磷酸化 FABP1 (Ser11) 抗体
货号: AF7055
描述: Rabbit polyclonal antibody to Phospho-FABP1 (Ser11)
应用: WB IHC
反应: Human, Mouse, Rat
预测: Pig, Horse, Rabbit, Dog
分子量: 14kDa; 14kD(Calculated).
蛋白号: P07148
RRID: AB_2843495

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(89%), Horse(100%), Rabbit(89%), Dog(100%)
克隆:
Polyclonal
特异性:
Phospho-FABP1 (Ser11) Antibody detects endogenous levels of FABP1 only when phosphorylated at Ser11.
RRID:
AB_2843495
引用格式: Affinity Biosciences Cat# AF7055, RRID:AB_2843495.
偶联:
Unconjugated.
纯化:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FABP 1; FABP1; FABPL; FABPL_HUMAN; Fatty Acid Binding Protein 1; Fatty acid binding protein 1 liver; Fatty Acid Binding Protein; Fatty acid-binding protein 1; Fatty acid-binding protein; Fatty acid-binding protein liver; L FABP; L-FABP; liver; Liver-type fatty acid-binding protein;

抗原和靶标

免疫原:
Uniprot:

P07148(FABPL_HUMAN) >>Visit HPA database.

基因/基因ID:
FABP1(2168)
序列:
MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Horse
100
Dog
100
Pig
89
Rabbit
89
Bovine
67
Sheep
67
Xenopus
67
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P07148 作为底物

Site PTM Type Enzyme
M1 Acetylation
S11 Phosphorylation
K33 Acetylation
K46 Acetylation
T51 Phosphorylation
T53 Phosphorylation
S56 Phosphorylation
S100 Phosphorylation
K121 Acetylation

研究背景

功能:

Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity).

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
蛋白家族:

Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

研究领域

· Organismal Systems > Endocrine system > PPAR signaling pathway.

· Organismal Systems > Digestive system > Fat digestion and absorption.

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