| 产品: | 磷酸化 FABP1 (Ser11) 抗体 |
| 货号: | AF7055 |
| 描述: | Rabbit polyclonal antibody to Phospho-FABP1 (Ser11) |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Horse, Rabbit, Dog |
| 分子量: | 14kDa; 14kD(Calculated). |
| 蛋白号: | P07148 |
| RRID: | AB_2843495 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF7055, RRID:AB_2843495.
展开/折叠
FABP 1; FABP1; FABPL; FABPL_HUMAN; Fatty Acid Binding Protein 1; Fatty acid binding protein 1 liver; Fatty Acid Binding Protein; Fatty acid-binding protein 1; Fatty acid-binding protein; Fatty acid-binding protein liver; L FABP; L-FABP; liver; Liver-type fatty acid-binding protein;
抗原和靶标
- P07148 FABPL_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P07148 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S11 | Phosphorylation | Uniprot | |
| K33 | Acetylation | Uniprot | |
| K46 | Acetylation | Uniprot | |
| T51 | Phosphorylation | Uniprot | |
| T53 | Phosphorylation | Uniprot | |
| S56 | Phosphorylation | Uniprot | |
| S100 | Phosphorylation | Uniprot | |
| K121 | Acetylation | Uniprot |
研究背景
Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity).
Cytoplasm.
Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
研究领域
· Organismal Systems > Endocrine system > PPAR signaling pathway.
· Organismal Systems > Digestive system > Fat digestion and absorption.
限制条款
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