产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF7092, RRID:AB_2843532.
展开/折叠
ACRP; Alpha catenin related protein; alpha CATU; Alpha catulin; Alpha-catenin-related protein; Alpha-catulin; alpha2 catulin; catenin (cadherin associated protein), alpha like 1; Catenin alpha like protein 1; Catenin alpha-like protein 1; catenin, alpha like 1; CLLP; CTNL1_HUMAN; CTNNAL1; Highly similar to ALPHA CATENIN;
抗原和靶标
Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.
- Q9UBT7 CTNL1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAASPGPAGVGGAGAVYGSGSSGFALDSGLEIKTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTDKTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDDKLMLLLEINKLIPLCHQLQTVTKTSLQNKVFLKVDKCITKTRSMMALLVQLLSLCYKLLKKLQMENNGWVSVTNKDTMDSKT
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9UBT7 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T40 | Phosphorylation | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| K84 | Ubiquitination | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| R161 | Methylation | Uniprot | |
| T240 | Phosphorylation | Uniprot | |
| S242 | Phosphorylation | Uniprot | |
| K258 | Ubiquitination | Uniprot | |
| K315 | Acetylation | Uniprot | |
| K373 | Ubiquitination | Uniprot | |
| S374 | Phosphorylation | Uniprot | |
| K394 | Ubiquitination | Uniprot | |
| K419 | Ubiquitination | Uniprot | |
| Y436 | Phosphorylation | Uniprot | |
| K439 | Ubiquitination | Uniprot | |
| K444 | Ubiquitination | Uniprot | |
| Y534 | Phosphorylation | Uniprot | |
| Y536 | Phosphorylation | Uniprot | |
| S538 | Phosphorylation | Uniprot | |
| S640 | Phosphorylation | Uniprot | |
| K681 | Ubiquitination | Uniprot |
研究背景
May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).
Cytoplasm>Cytoskeleton. Cell membrane>Peripheral membrane protein.
Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.
Interacts with ARHGEF1.
Belongs to the vinculin/alpha-catenin family.
限制条款
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