产品: 磷酸化 Semaphorin 4B (Ser809) 抗体
货号: AF7098
描述: Rabbit polyclonal antibody to Phospho-Semaphorin 4B (Ser809)
应用: WB IHC IF/ICC
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
分子量: 105KD; 93kD(Calculated).
蛋白号: Q9NPR2
RRID: AB_2843538

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   规格 价格 库存
 100ul RMB¥ 2800 现货
 200ul RMB¥ 3800 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(100%), Bovine(90%), Horse(100%), Sheep(90%), Rabbit(90%), Dog(100%), Xenopus(100%)
克隆:
Polyclonal
特异性:
Phospho-Semaphorin 4B (Ser809) Antibody detects endogenous levels of Semaphorin 4B only when phosphorylated at Ser809.
RRID:
AB_2843538
引用格式: Affinity Biosciences Cat# AF7098, RRID:AB_2843538.
偶联:
Unconjugated.
纯化:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Sema domain immunoglobulin domain (Ig) transmembrane domain (TM) and short cytoplasmic domain (semaphorin) 4B; Sema domain immunoglobulin domain (Ig) transmembrane domain (TM) and short cytoplasmic domain 4B; SEMA4B; SEMAC; Semaphorin 4B; SemC; KIAA1745; MGC131831; SEM4B_HUMAN.

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MLRTAMGLRSWLAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVGPRVHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGEFQCWSLEEGFQQLVASYCPEVVEDGVADQTDEGGSVPVIISTSRVSAPAGGKASWGADRSYWKEFLVMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLPPETRPLNGLGPPSTPLDHRGYQSLSDSPPGSRVFTESEKRPLSIQDSFVEVSPVCPRPRVRLGSEIRDSVV

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Dog
100
Xenopus
100
Bovine
90
Sheep
90
Rabbit
90
Chicken
70
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9NPR2 作为底物

Site PTM Type Enzyme
N64 N-Glycosylation
Y65 Phosphorylation
T66 Phosphorylation
K403 Acetylation
N405 N-Glycosylation
S694 Phosphorylation
K740 Ubiquitination
K744 Ubiquitination
T764 Phosphorylation
S774 Phosphorylation
T775 Phosphorylation
Y782 Phosphorylation
S784 Phosphorylation
S786 Phosphorylation
S788 Phosphorylation
T796 Phosphorylation
K800 Ubiquitination
S804 Phosphorylation
S808 Phosphorylation
S813 Phosphorylation
S825 Phosphorylation
S830 Phosphorylation

研究背景

功能:

Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.

细胞定位:

Membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
蛋白家族:

Belongs to the semaphorin family.

研究领域

· Organismal Systems > Development > Axon guidance.   (View pathway)

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