| 产品: | 磷酸化 LDHA (Tyr10) 抗体 |
| 货号: | AF7172 |
| 描述: | Rabbit polyclonal antibody to Phospho-LDHA (Tyr10) |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Sheep, Rabbit |
| 分子量: | 37kDa; 37kD(Calculated). |
| 蛋白号: | P00338 |
| RRID: | AB_2843612 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF7172, RRID:AB_2843612.
展开/折叠
Cell proliferation-inducing gene 19 protein; L lactate dehydrogenase A chain; Lactate dehydrogenase A; LDH A; LDH M; LDH muscle subunit; LDH1; LDH5; LDHA; PIG 19; PIG19; Renal carcinoma antigen NY-REN-59;
抗原和靶标
- P00338 LDHA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P00338 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| T3 | Phosphorylation | Uniprot | |
| K5 | Acetylation | Uniprot | |
| K5 | Methylation | Uniprot | |
| K5 | Ubiquitination | Uniprot | |
| Y10 | Phosphorylation | P11362 (FGFR1) , P04626 (ERBB2) , P12931 (SRC) | Uniprot |
| K14 | Acetylation | Uniprot | |
| K14 | Sumoylation | Uniprot | |
| K14 | Ubiquitination | Uniprot | |
| T18 | Phosphorylation | Uniprot | |
| K22 | Acetylation | Uniprot | |
| K57 | Acetylation | Uniprot | |
| K57 | Ubiquitination | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| T74 | Phosphorylation | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| K81 | Acetylation | Uniprot | |
| K81 | Ubiquitination | Uniprot | |
| Y83 | Phosphorylation | P11362 (FGFR1) | Uniprot |
| S89 | Phosphorylation | Uniprot | |
| K90 | Ubiquitination | Uniprot | |
| T95 | Phosphorylation | Uniprot | |
| K118 | Acetylation | Uniprot | |
| K118 | Methylation | Uniprot | |
| K118 | Ubiquitination | Uniprot | |
| K126 | Acetylation | Uniprot | |
| K126 | Ubiquitination | Uniprot | |
| Y127 | Phosphorylation | Uniprot | |
| S128 | Phosphorylation | Uniprot | |
| K132 | Acetylation | Uniprot | |
| K132 | Ubiquitination | Uniprot | |
| Y145 | Phosphorylation | Uniprot | |
| K155 | Ubiquitination | Uniprot | |
| R157 | Methylation | Uniprot | |
| S161 | Phosphorylation | Uniprot | |
| S167 | Phosphorylation | Uniprot | |
| R169 | Methylation | Uniprot | |
| Y172 | Phosphorylation | Uniprot | |
| S184 | Phosphorylation | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| K222 | Acetylation | Uniprot | |
| K222 | Ubiquitination | Uniprot | |
| K224 | Acetylation | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| K228 | Acetylation | Uniprot | |
| K228 | Ubiquitination | Uniprot | |
| K232 | Acetylation | Uniprot | |
| K232 | Ubiquitination | Uniprot | |
| S237 | Phosphorylation | Uniprot | |
| Y239 | Phosphorylation | Uniprot | |
| K243 | Acetylation | Uniprot | |
| K243 | Ubiquitination | Uniprot | |
| K245 | Ubiquitination | Uniprot | |
| T248 | Phosphorylation | P06493 (CDK1) | Uniprot |
| S249 | Phosphorylation | Uniprot | |
| R269 | Methylation | Uniprot | |
| K278 | Acetylation | Uniprot | |
| K278 | Methylation | Uniprot | |
| K278 | Ubiquitination | Uniprot | |
| K284 | Ubiquitination | Uniprot | |
| K305 | Ubiquitination | Uniprot | |
| T309 | Phosphorylation | Uniprot | |
| S310 | Phosphorylation | Uniprot | |
| K317 | Ubiquitination | Uniprot | |
| K318 | Acetylation | Uniprot | |
| K318 | Ubiquitination | Uniprot | |
| S319 | Phosphorylation | Uniprot | |
| T322 | Phosphorylation | Uniprot | |
| K328 | Acetylation | Uniprot | |
| K328 | Sumoylation | Uniprot | |
| K328 | Ubiquitination | Uniprot |
研究背景
ISGylated.
Cytoplasm.
Homotetramer.
Belongs to the LDH/MDH superfamily. LDH family.
研究领域
· Environmental Information Processing > Signal transduction > HIF-1 signaling pathway. (View pathway)
· Human Diseases > Cancers: Overview > Central carbon metabolism in cancer. (View pathway)
· Metabolism > Carbohydrate metabolism > Glycolysis / Gluconeogenesis.
· Metabolism > Amino acid metabolism > Cysteine and methionine metabolism.
· Metabolism > Carbohydrate metabolism > Pyruvate metabolism.
· Metabolism > Carbohydrate metabolism > Propanoate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Endocrine system > Glucagon signaling pathway.
限制条款
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