(2)
(4)
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF4410, RRID:AB_2844475.
展开/折叠
FOS L1; FOS like antigen 1; Fos related antigen 1; Fos-related antigen 1; FOSL 1; FOSL1; FOSL1 protein; FOSL1_HUMAN; FRA 1; FRA-1;
抗原和靶标
- P15407 FOSL1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLGPSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKEGDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPSTPEPCASAHRKSSSSSGDPSSDPLGSPTLLAL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P15407 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R66 | Methylation | Uniprot | |
| T69 | Phosphorylation | Uniprot | |
| S74 | Phosphorylation | Uniprot | |
| R79 | Methylation | Uniprot | |
| R84 | Methylation | Uniprot | |
| S101 | Phosphorylation | Uniprot | |
| K144 | Ubiquitination | Uniprot | |
| T183 | Phosphorylation | Uniprot | |
| S191 | Phosphorylation | Uniprot | |
| T217 | Phosphorylation | Uniprot | |
| T223 | Phosphorylation | Q04759 (PRKCQ) | Uniprot |
| T227 | Phosphorylation | Uniprot | |
| T230 | Phosphorylation | Q04759 (PRKCQ) | Uniprot |
| T240 | Phosphorylation | Uniprot | |
| S246 | Phosphorylation | Uniprot | |
| S251 | Phosphorylation | Uniprot | |
| S252 | Phosphorylation | Uniprot | |
| S253 | Phosphorylation | Uniprot | |
| S254 | Phosphorylation | Uniprot | |
| S265 | Phosphorylation | Q04759 (PRKCQ) | Uniprot |
| T267 | Phosphorylation | Uniprot |
研究背景
Nucleus.
Heterodimer.
Belongs to the bZIP family. Fos subfamily.
研究领域
· Environmental Information Processing > Signal transduction > Wnt signaling pathway. (View pathway)
· Human Diseases > Infectious diseases: Viral > HTLV-I infection.
· Organismal Systems > Development > Osteoclast differentiation. (View pathway)
· Organismal Systems > Immune system > IL-17 signaling pathway. (View pathway)
文献引用
Application: WB Species: Mice Sample: MC3T3-E1 cells
Application: WB Species: Mice Sample: MC3T3-E1 cells
限制条款
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