产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF4466, RRID:AB_2844523.
展开/折叠
CARS cyclophilin; CARS Cyp; CARS-cyclophilin; CARS-Cyp; CASP 10; CASP10; Clk associating RS cyclophilin; Clk-associating RS-cyclophilin; Cyclophilin G; CyclophilinG; CYP; MGC133241; Peptidyl prolyl cis trans isomerase G; Peptidyl prolyl isomerase G (cyclophilin G); Peptidyl prolyl isomerase G; Peptidyl-prolyl cis-trans isomerase G; Peptidyl-prolyl isomerase G; Peptidylprolyl isomerase G (cyclophilin G); Peptidylprolyl isomerase G; PPIase G; Ppig; PPIG_HUMAN; Rotamase G; RotamaseG; SCAF10; SR cyclophilin; SR cyp; SR related CTD associated factor 10; SR-cyclophilin; SR-cyp; SRcyp;
抗原和靶标
- Q13427 PPIG_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDKSG
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q13427 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K158 | Ubiquitination | Uniprot | |
| S173 | Phosphorylation | Uniprot | |
| K182 | Ubiquitination | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| S195 | Phosphorylation | Uniprot | |
| S196 | Phosphorylation | Uniprot | |
| S197 | Phosphorylation | Uniprot | |
| S198 | Phosphorylation | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| S200 | Phosphorylation | Uniprot | |
| S201 | Phosphorylation | Uniprot | |
| S202 | Phosphorylation | Uniprot | |
| S204 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| S207 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| S212 | Phosphorylation | Uniprot | |
| S214 | Phosphorylation | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| S219 | Phosphorylation | Uniprot | |
| T223 | Phosphorylation | Uniprot | |
| S254 | Phosphorylation | Uniprot | |
| S256 | Phosphorylation | Uniprot | |
| S257 | Phosphorylation | Uniprot | |
| S259 | Phosphorylation | Uniprot | |
| S290 | Phosphorylation | Uniprot | |
| S315 | Phosphorylation | Uniprot | |
| Y320 | Phosphorylation | Uniprot | |
| T343 | Phosphorylation | Uniprot | |
| S345 | Phosphorylation | Uniprot | |
| S347 | Phosphorylation | Uniprot | |
| S349 | Phosphorylation | Uniprot | |
| S356 | Phosphorylation | Uniprot | |
| T358 | Phosphorylation | Uniprot | |
| S375 | Phosphorylation | Uniprot | |
| S376 | Phosphorylation | Uniprot | |
| S386 | Phosphorylation | Uniprot | |
| S397 | Phosphorylation | Uniprot | |
| T407 | Phosphorylation | Uniprot | |
| S413 | Phosphorylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| S431 | Phosphorylation | Uniprot | |
| S433 | Phosphorylation | Uniprot | |
| S442 | Phosphorylation | Uniprot | |
| K447 | Acetylation | Uniprot | |
| K449 | Acetylation | Uniprot | |
| K459 | Ubiquitination | Uniprot | |
| K463 | Ubiquitination | Uniprot | |
| S487 | Phosphorylation | Uniprot | |
| S489 | Phosphorylation | Uniprot | |
| S527 | Phosphorylation | Uniprot | |
| S544 | Phosphorylation | Uniprot | |
| S546 | Phosphorylation | Uniprot | |
| T552 | Phosphorylation | Uniprot | |
| Y558 | Phosphorylation | Uniprot | |
| S560 | Phosphorylation | Uniprot | |
| S566 | Phosphorylation | Uniprot | |
| S568 | Phosphorylation | Uniprot | |
| S572 | Phosphorylation | Uniprot | |
| S587 | Phosphorylation | Uniprot | |
| T611 | Phosphorylation | Uniprot | |
| S628 | Phosphorylation | Uniprot | |
| S630 | Phosphorylation | Uniprot | |
| S631 | Phosphorylation | Uniprot | |
| S638 | Phosphorylation | Uniprot | |
| S666 | Phosphorylation | Uniprot | |
| S673 | Phosphorylation | Uniprot | |
| S674 | Phosphorylation | Uniprot | |
| S677 | Phosphorylation | Uniprot | |
| S687 | Phosphorylation | Uniprot | |
| S690 | Phosphorylation | Uniprot | |
| S696 | Phosphorylation | Uniprot | |
| S716 | Phosphorylation | Uniprot | |
| S717 | Phosphorylation | Uniprot | |
| K720 | Acetylation | Uniprot | |
| K724 | Acetylation | Uniprot | |
| S744 | Phosphorylation | Uniprot | |
| S745 | Phosphorylation | Uniprot | |
| T748 | Phosphorylation | Uniprot | |
| S753 | Phosphorylation | Uniprot |
研究背景
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.
Nucleus matrix. Nucleus speckle.
Note: Colocalizes with RNA splicing factors at nuclear speckles.
Ubiquitous.
Interacts with CLK1, PNN and with the phosphorylated C-terminal domain of RNA polymerase II.
The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.
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